Sporothrix brasiliensis, S. globosa, and S. mexicana, three new Sporothrix species of clinical interest

Rita Marimon, Josep Cano, Josepa Gené, Deanna A. Sutton, Masako Kawasaki, Josep Guarro

Research output: Contribution to journalArticle

297 Scopus citations

Abstract

Sporothrix schenckii is the species responsible for sporotrichosis, a fungal infection caused by the traumatic implantation of this dimorphic fungus. Recent molecular studies have demonstrated that this species constitutes a complex of numerous phylogenetic species. Since the delineation of such species could be of extreme importance from a clinical point of view, we have studied a total of 127 isolates, most of which were received as S. schenckii, including the available type strains of species currently considered synonyms, and also some close morphological species. We have phenotypically characterized all these isolates using different culture media, growth rates at different temperatures, and numerous nutritional tests and compared their calmodulin gene sequences. The molecular analysis revealed that Sporothrix albicans, S. inflata, and S. schenckii van luriei are species that are clearly different from S. schenckii. The combination of these phenetic and genetic approaches allowed us to propose the new species Sporothrix brasiliensis, S. globosa, and S. mexicana. The key phenotypic features for recognizing these species are the morphology of the sessile pigmented conidia, growth at 30, 35, and 37°C, and the assimilation of sucrose, raffinose, and ribitol.

Original languageEnglish (US)
Pages (from-to)3198-3206
Number of pages9
JournalJournal of clinical microbiology
Volume45
Issue number10
DOIs
StatePublished - Oct 2007

ASJC Scopus subject areas

  • Microbiology (medical)

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