Spontaneous neoplasia in the baboon (Papio spp.)

Rachel E. Cianciolo, Stephanie D. Butler, Jeffery S. Eggers, Edward J. Dick, M. Michelle Leland, Melissa De La Garza, Kathleen M. Brasky, Larry B. Cummins, Gene B. Hubbard

Research output: Contribution to journalArticlepeer-review

41 Scopus citations


Background: There are several comprehensive reviews of spontaneous neoplasia in non-human primates that compile individual cases or small numbers of cases, but do not provide statistical analysis of tumor incidence, demographics, or epidemiology. Methods: This paper reports all spontaneous neoplasms (n= 363) diagnosed over a 15-year period in a baboon colony with an average annual colony population of 4000. Result: A total of 363 spontaneous neoplasms were diagnosed in 313 baboons: 77 cases were males (25%) and 236 were females (75%); ages ranged from 1 month to 33 years (mean 16.5, median 17). Conclusion: Theorgan systems affected in descending order of number of neoplasms were hematopoietic organs (n = 101, 28%), urogenital tract (n = 78, 21%), integument (n = 43, 12%), alimentary tract (n = 43, 12%), endocrine organs (n = 40, 11%), nervous system (n = 33, 9%), musculoskeletal system (n = 5, 1%), and respiratory system (n = 4, 1%). Malignant cases numbered 171 (47%); 192 (53%) cases were benign.

Original languageEnglish (US)
Pages (from-to)61-79
Number of pages19
JournalJournal of medical primatology
Issue number2
StatePublished - Apr 2007
Externally publishedYes


  • Cancer
  • Epidemiology
  • Non-human primate
  • Tumors

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)


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