TY - JOUR
T1 - Spontaneous neoplasia in the baboon (Papio spp.)
AU - Cianciolo, Rachel E.
AU - Butler, Stephanie D.
AU - Eggers, Jeffery S.
AU - Dick, Edward J.
AU - Leland, M. Michelle
AU - De La Garza, Melissa
AU - Brasky, Kathleen M.
AU - Cummins, Larry B.
AU - Hubbard, Gene B.
PY - 2007/4
Y1 - 2007/4
N2 - Background: There are several comprehensive reviews of spontaneous neoplasia in non-human primates that compile individual cases or small numbers of cases, but do not provide statistical analysis of tumor incidence, demographics, or epidemiology. Methods: This paper reports all spontaneous neoplasms (n= 363) diagnosed over a 15-year period in a baboon colony with an average annual colony population of 4000. Result: A total of 363 spontaneous neoplasms were diagnosed in 313 baboons: 77 cases were males (25%) and 236 were females (75%); ages ranged from 1 month to 33 years (mean 16.5, median 17). Conclusion: Theorgan systems affected in descending order of number of neoplasms were hematopoietic organs (n = 101, 28%), urogenital tract (n = 78, 21%), integument (n = 43, 12%), alimentary tract (n = 43, 12%), endocrine organs (n = 40, 11%), nervous system (n = 33, 9%), musculoskeletal system (n = 5, 1%), and respiratory system (n = 4, 1%). Malignant cases numbered 171 (47%); 192 (53%) cases were benign.
AB - Background: There are several comprehensive reviews of spontaneous neoplasia in non-human primates that compile individual cases or small numbers of cases, but do not provide statistical analysis of tumor incidence, demographics, or epidemiology. Methods: This paper reports all spontaneous neoplasms (n= 363) diagnosed over a 15-year period in a baboon colony with an average annual colony population of 4000. Result: A total of 363 spontaneous neoplasms were diagnosed in 313 baboons: 77 cases were males (25%) and 236 were females (75%); ages ranged from 1 month to 33 years (mean 16.5, median 17). Conclusion: Theorgan systems affected in descending order of number of neoplasms were hematopoietic organs (n = 101, 28%), urogenital tract (n = 78, 21%), integument (n = 43, 12%), alimentary tract (n = 43, 12%), endocrine organs (n = 40, 11%), nervous system (n = 33, 9%), musculoskeletal system (n = 5, 1%), and respiratory system (n = 4, 1%). Malignant cases numbered 171 (47%); 192 (53%) cases were benign.
KW - Cancer
KW - Epidemiology
KW - Non-human primate
KW - Tumors
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U2 - 10.1111/j.1600-0684.2006.00202.x
DO - 10.1111/j.1600-0684.2006.00202.x
M3 - Article
C2 - 17493137
AN - SCOPUS:33947380507
SN - 0047-2565
VL - 36
SP - 61
EP - 79
JO - Journal of Medical Primatology
JF - Journal of Medical Primatology
IS - 2
ER -