Spontaneous mutation results in loss of the cytadhesin (P1) of Mycoplasma pneumoniae

C. J. Su, A. Chavoya, J. B. Baseman

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

The cytadhesin (P1) structural gene of a spontaneous mutant of Mycoplasma pneumoniae which displayed a P1-negative phenotype was analyzed. An extra adenine was discovered in a stretch of normally seven adenines near the N-terminal region of the mutant P1 structural gene. The frameshift mutation resulted in the early termination of protein translation. Possible causes of the mutation are discussed.

Original languageEnglish (US)
Pages (from-to)3237-3239
Number of pages3
JournalInfection and immunity
Volume57
Issue number10
StatePublished - 1989

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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