Spontaneous heart disease in the adult chimpanzee (Pan troglodytes)

Brittany M. Seiler, Edward J. Dick, Rodolfo Guardado-Mendoza, John L. Vandeberg, Jeff T. Williams, James N. Mubiru, Gene B. Hubbard

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Background: A high incidence of heart disease, especially idiopathic cardiomyopathy (IC), is seen in chimpanzees (Pan troglodytes). Methods: We reviewed clinical records and necropsy reports of 87 adult chimpanzees for possible causes of heart disease/IC. We examined age, sex, cause of death, weight, diet, environment, infectious diseases, experimental uses and clinical pathology. Results: The overall prevalence of heart disease in chimpanzees was 67.81%; the prevalence of IC was 51.72%. The prevalence of IC was significantly higher in males (60.32%) than that in females (29.17%, P = 0.009). The prevalence of other heart disease was higher in females (25%) than that in males (12.70%, P = 0.165). Heart failure occurred in 47.13% of chimpanzees. Heart disease was the primary cause of death in 34.49% of chimpanzees; 29.88% died of unknown causes. Conclusions: We found no evidence that diet, environment, viral agents, experimental use or disease exposure contributed to the deaths resulting from IC in chimpanzees.

Original languageEnglish (US)
Pages (from-to)51-58
Number of pages8
JournalJournal of Medical Primatology
Volume38
Issue number1
DOIs
StatePublished - 2009
Externally publishedYes

Fingerprint

Pan troglodytes
heart diseases
Heart Diseases
cardiomyopathy
Cardiomyopathies
death
Cause of Death
Diet
Clinical Pathology
heart failure
diet
infectious diseases
Communicable Diseases
necropsy
Heart Failure
Weights and Measures
incidence
gender
Incidence

Keywords

  • Ape
  • Arteriosclerosis
  • Atherosclerosis
  • Cardiomyopathy
  • Non-human primate

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

Cite this

Seiler, B. M., Dick, E. J., Guardado-Mendoza, R., Vandeberg, J. L., Williams, J. T., Mubiru, J. N., & Hubbard, G. B. (2009). Spontaneous heart disease in the adult chimpanzee (Pan troglodytes). Journal of Medical Primatology, 38(1), 51-58. https://doi.org/10.1111/j.1600-0684.2008.00307.x

Spontaneous heart disease in the adult chimpanzee (Pan troglodytes). / Seiler, Brittany M.; Dick, Edward J.; Guardado-Mendoza, Rodolfo; Vandeberg, John L.; Williams, Jeff T.; Mubiru, James N.; Hubbard, Gene B.

In: Journal of Medical Primatology, Vol. 38, No. 1, 2009, p. 51-58.

Research output: Contribution to journalArticle

Seiler, BM, Dick, EJ, Guardado-Mendoza, R, Vandeberg, JL, Williams, JT, Mubiru, JN & Hubbard, GB 2009, 'Spontaneous heart disease in the adult chimpanzee (Pan troglodytes)', Journal of Medical Primatology, vol. 38, no. 1, pp. 51-58. https://doi.org/10.1111/j.1600-0684.2008.00307.x
Seiler BM, Dick EJ, Guardado-Mendoza R, Vandeberg JL, Williams JT, Mubiru JN et al. Spontaneous heart disease in the adult chimpanzee (Pan troglodytes). Journal of Medical Primatology. 2009;38(1):51-58. https://doi.org/10.1111/j.1600-0684.2008.00307.x
Seiler, Brittany M. ; Dick, Edward J. ; Guardado-Mendoza, Rodolfo ; Vandeberg, John L. ; Williams, Jeff T. ; Mubiru, James N. ; Hubbard, Gene B. / Spontaneous heart disease in the adult chimpanzee (Pan troglodytes). In: Journal of Medical Primatology. 2009 ; Vol. 38, No. 1. pp. 51-58.
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