Spontaneous electrical potentials and pituitary hormone (MSH) secretion

M. Duff Davis, Mac E. Hadley

Research output: Contribution to journalArticle

25 Scopus citations

Abstract

CELLULAR secretions from either exocrine or endocrine glands are regulated in most cases by hormonal or neurohormonal agents. These chemical messengers interact with cellular receptors to stimulate a particular secretory response. In general, it would seem that changes in the transmembrane electrical potential of the secretory unit is in some way intimately involved in this stimulus-secretion coupling1. Here we provide evidence of cellular secretion resulting from spontaneous electrical activity (most probably depolarisations) after removal of a previously inhibitory stimulus.

Original languageEnglish (US)
Pages (from-to)422-423
Number of pages2
JournalNature
Volume261
Issue number5559
DOIs
StatePublished - Dec 1 1976

    Fingerprint

ASJC Scopus subject areas

  • General

Cite this