CELLULAR secretions from either exocrine or endocrine glands are regulated in most cases by hormonal or neurohormonal agents. These chemical messengers interact with cellular receptors to stimulate a particular secretory response. In general, it would seem that changes in the transmembrane electrical potential of the secretory unit is in some way intimately involved in this stimulus-secretion coupling1. Here we provide evidence of cellular secretion resulting from spontaneous electrical activity (most probably depolarisations) after removal of a previously inhibitory stimulus.
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