Abstract
Objective: The purpose of this study was to use a prototype side-illuminating near-infrared spectroscopy (NIRS) nasogastric probe to continuously measure changes in gastric tissue oxygen saturation (Sto2) in a pig hemorrhage model. Methods: Swine (n = 12; 6 per group) underwent laparotomy and placement of a gastric NIRS probe, jejunal tonometer, superior mesenteric artery (SMA) flow probe, and a portal vein catheter. Animals underwent hemorrhage (28 mL/kg) t = 0 to 20 minutes (where t = time). Pigs in group I were resuscitated (t = 20-40 minutes) with lactated Ringer's solution (84 mL/kg), whereas group II had no resuscitation. Results: A significant decrease in mean arterial pressure and SMA flow was observed after hemorrhage. SMA flow significantly correlated in group I with both NIRS Sto2 (r = 0.58, p = 0.0001) and regional CO2 (r = -0.54, p = 0.0001). In group II, superior mesenteric flow correlated with NIRS Sto2 (r = 0.30, p = 0.03), but not regional CO2 (r = -0.23, p = 0.09). Conclusion: Direct measurement of tissue oxygen saturation with a prototype side-illuminating near-infrared spectroscopy gastric probe appeared to rapidly reflect changes in splanchnic perfusion.
Original language | English (US) |
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Pages (from-to) | 629-635 |
Number of pages | 7 |
Journal | Journal of Trauma - Injury, Infection and Critical Care |
Volume | 50 |
Issue number | 4 |
DOIs | |
State | Published - Jan 1 2001 |
Keywords
- Hemorrhagic shock
- Near-infrared spectroscopy
- Resuscitation
- Splanchnic perfusion
ASJC Scopus subject areas
- Surgery
- Critical Care and Intensive Care Medicine