Spiral waves and intracellular calcium signalling

JD D. Lechleiter; DE E. Clapham

doi:10.1016/S0928-4257(05)80016-6

Spiral waves and intracellular calcium signalling

JD D. Lechleiter, DE E. Clapham

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

Confocal imaging of intracellular Ca²⁺ brings a new level of resolution to the study of hormonal control of intracellular Ca²⁺ release. This approach has demonstrated the existence of pulsatile circular and spiral waves of Ca⁺ release induced by receptor activation. The data obtained by confocal imaging support a new framework for understanding intracellular Ca²⁺ signalling. The goal of this chapter is to review our data on the complexity of intracellular Ca²⁺ release in Xenopus oocytes, introduce the concept of Ca²⁺ excitability as a model for Ca²⁺ release and discuss the implications for encoding intracellular signal information.

Original language	English (US)
Pages (from-to)	123-128
Number of pages	6
Journal	Journal of Physiology - Paris
Volume	86
Issue number	1-3
DOIs	https://doi.org/10.1016/S0928-4257(05)80016-6
State	Published - 1992
Externally published	Yes

Keywords

IP
Xenopus oocytes
confocal microscopy
excitable media

ASJC Scopus subject areas

Physiology (medical)
General Neuroscience

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10.1016/S0928-4257(05)80016-6

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title = "Spiral waves and intracellular calcium signalling",

abstract = "Confocal imaging of intracellular Ca2+ brings a new level of resolution to the study of hormonal control of intracellular Ca2+ release. This approach has demonstrated the existence of pulsatile circular and spiral waves of Ca+ release induced by receptor activation. The data obtained by confocal imaging support a new framework for understanding intracellular Ca2+ signalling. The goal of this chapter is to review our data on the complexity of intracellular Ca2+ release in Xenopus oocytes, introduce the concept of Ca2+ excitability as a model for Ca2+ release and discuss the implications for encoding intracellular signal information.",

keywords = "IP, Xenopus oocytes, confocal microscopy, excitable media",

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year = "1992",

doi = "10.1016/S0928-4257(05)80016-6",

language = "English (US)",

volume = "86",

pages = "123--128",

journal = "Journal of Physiology - Paris",

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T1 - Spiral waves and intracellular calcium signalling

AU - Lechleiter, JD D.

AU - Clapham, DE E.

PY - 1992

Y1 - 1992

N2 - Confocal imaging of intracellular Ca2+ brings a new level of resolution to the study of hormonal control of intracellular Ca2+ release. This approach has demonstrated the existence of pulsatile circular and spiral waves of Ca+ release induced by receptor activation. The data obtained by confocal imaging support a new framework for understanding intracellular Ca2+ signalling. The goal of this chapter is to review our data on the complexity of intracellular Ca2+ release in Xenopus oocytes, introduce the concept of Ca2+ excitability as a model for Ca2+ release and discuss the implications for encoding intracellular signal information.

AB - Confocal imaging of intracellular Ca2+ brings a new level of resolution to the study of hormonal control of intracellular Ca2+ release. This approach has demonstrated the existence of pulsatile circular and spiral waves of Ca+ release induced by receptor activation. The data obtained by confocal imaging support a new framework for understanding intracellular Ca2+ signalling. The goal of this chapter is to review our data on the complexity of intracellular Ca2+ release in Xenopus oocytes, introduce the concept of Ca2+ excitability as a model for Ca2+ release and discuss the implications for encoding intracellular signal information.

KW - IP

KW - Xenopus oocytes

KW - confocal microscopy

KW - excitable media

UR - https://www.scopus.com/pages/publications/0027067875

UR - https://www.scopus.com/inward/citedby.url?scp=0027067875&partnerID=8YFLogxK

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DO - 10.1016/S0928-4257(05)80016-6

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AN - SCOPUS:0027067875

SN - 0928-4257

VL - 86

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EP - 128

JO - Journal of Physiology - Paris

JF - Journal of Physiology - Paris

IS - 1-3

ER -

Spiral waves and intracellular calcium signalling

Abstract

Keywords

ASJC Scopus subject areas

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