Abstract
Among 50 patients with small cell bronchogenic carcinoma who were placed on a protocol of combined chemotherapy and radiation therapy, seven patients developed recurrence in the spinal cord. Five cases terminated in paraplegia and death. One patient with pontine recurrence recovered with local radiation therapy. One patient, diagnosed early, responded to local radiation therapy and is ambulatory. Methods of diagnosis were myelogram, computerized axial tomography, cerebro spinal fluid, chemistry and cytologies. The poor prognosis and the difficulty of diagnosis suggest that we should evaluate prophylactic therapy of the entire cranio-spinal axis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 349-356 |
| Number of pages | 8 |
| Journal | International Journal of Radiation Oncology, Biology, Physics |
| Volume | 10 |
| Issue number | 3 |
| DOIs | |
| State | Published - Mar 1984 |
| Externally published | Yes |
Keywords
- Recurrence
- Small cell lung cancer
- Spinal cord
ASJC Scopus subject areas
- Radiation
- Oncology
- Radiology Nuclear Medicine and imaging
- Cancer Research
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Cite this
Holoye, P., Libnoch, J., Cox, J., Kun, L., Byhardt, R., Almagro, U., McClelland, S., & Chintapali, K. (1984). Spinal cord metastasis in small cell carcinoma of the lung. International Journal of Radiation Oncology, Biology, Physics, 10(3), 349-356. https://doi.org/10.1016/0360-3016(84)90053-1