Spike Frequency Adaptation Affects the Synchronization Properties of Networks of Cortical Oscillators

Sharon M. Crook, G. Bard Ermentrout, James M. Bower

Research output: Contribution to journalArticle

84 Scopus citations

Abstract

Oscillations in many regions of the cortex have common temporal characteristics with dominant frequencies centered around the 40 Hz (gamma) frequency range and the 5-10 Hz (theta) frequency range. Experimental results also reveal spatially synchronous oscillations, which are stimulus dependent (Gray & Singer, 1987; Gray, König, Engel, & Singer, 1989; Engel, König, Kreiter, Schillen, & Singer, 1992). This rhythmic activity suggests that the coherence of neural populations is a crucial feature of cortical dynamics (Gray, 1994). Using both simulations and a theoretical coupled oscillator approach, we demonstrate that the spike frequency adaptation seen in many pyramidal cells plays a subtle but important role in the dynamics of cortical networks. Without adaptation, excitatory connections among model pyramidal cells are desynchronizing. However, the slow processes associated with adaptation encourage stable synchronous behavior.

Original languageEnglish (US)
Pages (from-to)837-854
Number of pages18
JournalNeural Computation
Volume10
Issue number4
DOIs
StatePublished - May 15 1998

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Cognitive Neuroscience

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