Southwestern Internal Medicine Conference: The endothelium - A key regulator of vascular tone

W. L. Henrich

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Emerging evidence suggests the endothelium produces several substances capable of locally regulating organ blood flow. Vasoactive prostaglandins, endothelium-derived relaxing factor, and endothelin are examples of these vasoactive substances. Abnormalities of endothelial function may contribute to the pathogenesis of disease in several circumstances, including hypertension, diabetes, and septicemia. Evidence for the endothelium as a regulator of regional perfusion and several of the endothelium-derived substances and their potential role in disease are reviewed.

Original languageEnglish (US)
Pages (from-to)319-328
Number of pages10
JournalAmerican Journal of the Medical Sciences
Volume302
Issue number5
DOIs
StatePublished - Jan 1 1991

Keywords

  • Endothelium
  • Regional perfusion

ASJC Scopus subject areas

  • Medicine(all)

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