Sodium transport: Inhibitory factor in sweat of patients with cystic fibrosis

John A. Mangos, Nona R. Mcsherry

Research output: Contribution to journalArticle

61 Scopus citations

Abstract

A factor inhibitory to sodium transport exists in the sweat of patients with cystic fibrosis of the pancreas. When the duct system of the rat parotid was perfused with sweat from patients, marked inhibition of sodium reabsorption was observed. Perfusion with sweat from normal subjects caused no change in sodium reabsorption. The factor thus demonstrated may be responsible for the increased sodium concentrations in the sweat of patients with cystic fibrosis.

Original languageEnglish (US)
Pages (from-to)135-136
Number of pages2
JournalScience
Volume158
Issue number3797
DOIs
StatePublished - Jan 1 1967

ASJC Scopus subject areas

  • General

Fingerprint Dive into the research topics of 'Sodium transport: Inhibitory factor in sweat of patients with cystic fibrosis'. Together they form a unique fingerprint.

  • Cite this