Six-minute walk test in Chagas cardiomyopathy

Lidiane Sousa, Fernando Antônio Botoni, Raquel R. Britto, Manoel Otávio da Costa Rocha, Antonio Lúcio Teixeira, Mauro Martins Teixeira, Adelina M. Reis, Bráulio Muzzi R. Oliveira, Antonio L. Ribeiro

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


We studied systematically, for the first time, the utility of the six-minute walk test (6MWT) in Chagas disease. The walked distance at 6MWT correlated negatively with the increased circulating levels of monocyte chemoattractant protein (MCP-1, r = - 0.358, p = 0.04) and natriuretic peptide type B (BNP, r = - 0.349, p = 0.04), as well as positively with ejection fraction deterioration (r = 0.451, p = 0.004), indicating that submaximal functional capacity of chagasic patients is related to the severity of the cardiopathy. 6MWT may constitute an auxiliary tool in the evaluation of the clinical status of Chagas disease patients.

Original languageEnglish (US)
Pages (from-to)139-141
Number of pages3
JournalInternational Journal of Cardiology
Issue number1
StatePublished - Mar 28 2008
Externally publishedYes


  • Chagas disease
  • Inflammation
  • Six-minute walk test

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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