Sintez belka i okislitel'naia aktivnost' mozga v usloviiakh kislorodnoǐ nedostatochnosti.

Translated title of the contribution: Protein synthesis and oxidative activity of the brain in oxygen deficiency

N. N. Bogolepov, E. L. Dovedova, A. P. Musatov, M. Khavka

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Biochemical and electron microscopic research methods showed disorders of the metabolism and the ultrastructure of the rat brain under the impact of experimental hypoxia and anoxia. Two to 3.5 hours after the exposure, the synthesis of protein in the neuronal fractions was impaired and the activity of the oxidative enzymes in the subfractions of synaptosomes and mitochondria was inhibited. The tissue ultrastructure was also impaired which was most pronounced in the synaptic processes of neurones. The data indicate fine morphochemical correlations at the subcellular level in the period immediately following post-hypoxic brain survival.

Translated title of the contributionProtein synthesis and oxidative activity of the brain in oxygen deficiency
Original languageRussian
Pages (from-to)1765-1769
Number of pages5
JournalZhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova
Volume83
Issue number12
StatePublished - 1983
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health

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