Simultaneous spectrophotometric and mechanical property characterization of skin

Leonid Bunegin, Jeffery B. Moore

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Citations (Scopus)

Abstract

Both reflectance spectroscopy and the determination Young's Modulus of skin have shown promise for identifying skin pathology. At present, these determinations are carried out using separate methodologies. This study demonstrates a new technology combining digital UV/VIS reflectance spectroscopy and vacuum aspiration for simultaneously determining the reflectance spectrum and mechanical properties of human skin tissue. A small hand held prototype device incorporating fiber-optic light guides into a vacuum channel was calibrated using various elastic materials subjected to increments of stress by vacuum from 0 to 25 in Hg. The intensity of a UV/VIS light beam reflected from the material at each vacuum increment was compared to the resulting material strain. The reflected beam was also spectrophotometrically analyzed. Skin types were similarly evaluated comparing normal and scar tissue and skin of various ages and coloration. An exponential relationship between reflected beam intensity and the amount of strain resulting from vacuum increments was observed. Young's Modulus (calculated from Aoki et. al equation) and spectra from normal skin and scar tissue were in agreement with previously published observations. Age related decreases in skin elasticity were also demonstrated. In the reflectance spectra, oxy and deoxy-hemoglobin absorbance bands were detected, becoming significantly enhanced at increased levels of vacuum. Melanin absorbance was also easily detected and appeared to correlate with skin coloration. Since superficial skin pathologies have characteristic spectroscopic and mechanical properties, this technique may provide a promising new approach for rapid, non-invasive method for the evaluation of skin lesions.

Original languageEnglish (US)
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6078
DOIs
StatePublished - 2006
EventPhotonic Therapeutics and Diagnostics II - San Jose, CA, United States
Duration: Jan 21 2006Jan 24 2006

Other

OtherPhotonic Therapeutics and Diagnostics II
CountryUnited States
CitySan Jose, CA
Period1/21/061/24/06

Fingerprint

Skin
Mechanical properties
Vacuum
Pathology
Tissue
Elastic moduli
Spectroscopy
Melanin
Hemoglobin
Ultraviolet radiation
Fiber optics
Elasticity

Keywords

  • Mechanical properties
  • Skin
  • Spectrophotometric
  • Young's Modulus

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Bunegin, L., & Moore, J. B. (2006). Simultaneous spectrophotometric and mechanical property characterization of skin. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 6078). [607807] https://doi.org/10.1117/12.644755

Simultaneous spectrophotometric and mechanical property characterization of skin. / Bunegin, Leonid; Moore, Jeffery B.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6078 2006. 607807.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Bunegin, L & Moore, JB 2006, Simultaneous spectrophotometric and mechanical property characterization of skin. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 6078, 607807, Photonic Therapeutics and Diagnostics II, San Jose, CA, United States, 1/21/06. https://doi.org/10.1117/12.644755
Bunegin L, Moore JB. Simultaneous spectrophotometric and mechanical property characterization of skin. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6078. 2006. 607807 https://doi.org/10.1117/12.644755
Bunegin, Leonid ; Moore, Jeffery B. / Simultaneous spectrophotometric and mechanical property characterization of skin. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 6078 2006.
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