Simulated nasoalveolar palatal defects: A canine model to study bone grafts

William J. Ehler, Robert E. Marx, John H. Cissik, Gene B. Hubbard

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


A simple, surgical technique to create a simulated nasoalveolar palatal defect in the canine is described. The procedure has been performed in 60 canines, and we have not experienced closure of the created clefts. The surgically created clefts had to fulfill five criteria: (1) bilateral maxillary alveolar clefts had to exist in each research animal; (2) each cleft had to have a 1-cm bony width; (3) a demonstrable oronasal communication had to be present; (4) each cleft had to be lined by healthy epithelialized mucosa; (5) there had to be functional teeth adjacent to each side of every cleft.

Original languageEnglish (US)
Pages (from-to)341-347
Number of pages7
JournalJournal of Investigative Surgery
Issue number4
StatePublished - 1990
Externally publishedYes


  • Alveolar cleft palatal defects
  • Bone grafts
  • Nasoalveolar

ASJC Scopus subject areas

  • Surgery


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