Sex differences in stroke incidence and survival in Hong Kong, 2000-2007

S. H. Wu, S. C. Ho, P. H. Chau, W. Goggins, A. Sham, J. Woo

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

Background: Few studies have examined the impact of sex across different age groups and over time on chronic diseases in Asia. The objective of this study was to explore the effect of sex across different age groups and over time on stroke incidence and 30-day case fatality in Hong Kong. Methods: Over 90% first hospitalizations for stroke in Hong Kong (from 2000 to 2007) were identified from the Clinical Management System of the Hospital Authority. Age-specific rate ratios (RRs; women to men) for incidence of first hospitalization and the 30-day case fatality were estimated based on Poisson regression models after adjustment for year of hospitalization. Results: Women below the age of 85 years had a lower incidence of first hospitalization than men, and the effect size varied with age [35-44 years: RR = 0.56, 95% confidence interval (CI) = 0.49-0.64; 45-54 years: 0.65, 0.53-0.79; 55-64 years: 0.58, 0.48-0.71; 65-74 years: 0.71, 0.58-0.85; 75-84 years: 0.83, 0.68-1.00)]. Women aged ≥85 years had a stroke incidence similar to men, but the adjusted 30-day case fatality was significantly higher than that of men aged ≥85 years (RR = 1.14, 95% CI = 1.05-1.23). Conclusions: Lower rates of incidence were observed in women than men aged 35-84 years in Hong Kong but short-term case fatality is greater in women aged ≥85 years.

Original languageEnglish (US)
Pages (from-to)69-75
Number of pages7
JournalNeuroepidemiology
Volume38
Issue number2
DOIs
StatePublished - Mar 1 2012
Externally publishedYes

Keywords

  • Cerebrovascular disease epidemiology
  • Prognosis
  • Sex

ASJC Scopus subject areas

  • Epidemiology
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Sex differences in stroke incidence and survival in Hong Kong, 2000-2007'. Together they form a unique fingerprint.

Cite this