Serum α-fetoprotein screening for hepatoblastoma in children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia

Carol L. Clericuzio; Emily Chen; Dawn Elizabeth McNeil; Timothy O'Connor; Elaine H. Zackai; Livija Medne; Gail Tomlinson; Michael DeBaun

doi:10.1067/S0022-3476(03)00306-8

Serum α-fetoprotein screening for hepatoblastoma in children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia

Carol L. Clericuzio
, Emily Chen
, Dawn Elizabeth McNeil
, Timothy O'Connor
, Elaine H. Zackai
, Livija Medne
, Gail Tomlinson
, Michael DeBaun

Department of Pediatrics

Research output: Contribution to journal › Article › peer-review

86 Scopus citations

Abstract

An elevated risk of hepatoblastoma for children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia is well established. We describe five children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia for whom serial serum α-fetoprotein screening, usually in combination with abdominal ultrasound, led to early detection of hepatoblastoma.

Original language	English (US)
Pages (from-to)	270-272
Number of pages	3
Journal	Journal of Pediatrics
Volume	143
Issue number	2
DOIs	https://doi.org/10.1067/S0022-3476(03)00306-8
State	Published - Aug 1 2003

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1067/S0022-3476(03)00306-8

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abstract = "An elevated risk of hepatoblastoma for children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia is well established. We describe five children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia for whom serial serum α-fetoprotein screening, usually in combination with abdominal ultrasound, led to early detection of hepatoblastoma.",

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AU - Clericuzio, Carol L.

AU - Chen, Emily

AU - McNeil, Dawn Elizabeth

AU - O'Connor, Timothy

AU - Zackai, Elaine H.

AU - Medne, Livija

AU - Tomlinson, Gail

AU - DeBaun, Michael

PY - 2003/8/1

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N2 - An elevated risk of hepatoblastoma for children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia is well established. We describe five children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia for whom serial serum α-fetoprotein screening, usually in combination with abdominal ultrasound, led to early detection of hepatoblastoma.

AB - An elevated risk of hepatoblastoma for children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia is well established. We describe five children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia for whom serial serum α-fetoprotein screening, usually in combination with abdominal ultrasound, led to early detection of hepatoblastoma.

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DO - 10.1067/S0022-3476(03)00306-8

M3 - Article

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Serum α-fetoprotein screening for hepatoblastoma in children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia

Abstract

ASJC Scopus subject areas

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