Serum α-fetoprotein screening for hepatoblastoma in children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia

Carol L. Clericuzio, Emily Chen, Dawn Elizabeth McNeil, Timothy O'Connor, Elaine H. Zackai, Livija Medne, Gail Tomlinson, Michael DeBaun

Research output: Contribution to journalArticlepeer-review

79 Scopus citations

Abstract

An elevated risk of hepatoblastoma for children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia is well established. We describe five children with Beckwith-Wiedemann syndrome or isolated hemihyperplasia for whom serial serum α-fetoprotein screening, usually in combination with abdominal ultrasound, led to early detection of hepatoblastoma.

Original languageEnglish (US)
Pages (from-to)270-272
Number of pages3
JournalJournal of Pediatrics
Volume143
Issue number2
DOIs
StatePublished - Aug 1 2003

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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