Serotipos y genotipos de virus dengue circulantes en Venezuela, 1990-1997.

Translated title of the contribution: Serotypes and genotypes of dengue virus circulating in Venezuela, 1990-1997

R. A. Salas, D. Tovar, A. Barreto, E. de Miller, K. Leitmeyer, R. Rico-Hesse

    Research output: Contribution to journalArticle

    20 Scopus citations

    Abstract

    Due to the increasing severity of hemorrhagic dengue epidemics during the last years in Venezuela, a retrospective analysis was conducted to identify the behaviour of the dengue virus serotypes circulating in the country and the molecular evolution of dengue virus serotype 2. The data presented here indicates that dengue virus serotypes 1, 2 and 4 are endemic in Venezuela, they circulate simultaneously around the year in the biggest urban cities, however, one particular serotype is predominant during an epidemic period and replaces the virus serotype dominant during the previous epidemic period. The increased severity of dengue fever since 1989 in Venezuela might be associated to the introduction of the Asiatic genotype of virus which replaced the autochthonous Caribbean genotype. The Asiatic genotype is recognised as a more virulent virus.

    Original languageSpanish
    Pages (from-to)33-37
    Number of pages5
    JournalActa científica venezolana
    Volume49 Suppl 1
    StatePublished - 1998

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    ASJC Scopus subject areas

    • Biochemistry, Genetics and Molecular Biology(all)
    • Environmental Science(all)
    • Agricultural and Biological Sciences(all)

    Cite this

    Salas, R. A., Tovar, D., Barreto, A., de Miller, E., Leitmeyer, K., & Rico-Hesse, R. (1998). Serotipos y genotipos de virus dengue circulantes en Venezuela, 1990-1997. Acta científica venezolana, 49 Suppl 1, 33-37.