@article{bcd8deb338c24fe284ed7d09b51dfd13,
title = "Serotonin decreases population spike amplitude in hippocampal cells through a pertussis toxin substrate",
abstract = "Activation of the serotonin1A receptor decreases CA1 population spike amplitude and inhibits forskolin-stimulated adenylate cyclase in rat hippocampus. Pretreatment of rats with pertussis toxin blocked both responses. Because the electrophysiological and biochemical responses to serotonin were correlated after pertussis toxin treatment, we conclude that both responses are mediated by a common regulatory protein, presumably Gi.",
keywords = "Adenylate cyclase, G protein, Hippocampus, Pertussis toxin, Population spike, Serotonin",
author = "Clarke, {William P.} and {De Vivo}, Michael and Beck, {Sheryl G.} and Saul Maayani and Joseph Goldfarb",
note = "Funding Information: This work was supported by NIH postdoctoral Training Grant DA-07135. a Pharmaceutical Manufacturers Association Foundation fellowship to M.D.V., and Grants DA-01875 from the National Institute on Drug Abuse. GM-34852 from the National Institute of General Medical Sciences. and MH-41917 from the National Institute of Mental Health. Data analyses were performed on the PROPHET Computer System, a national resource supported by the Biochemical Research Technology Program. Division of Research Resources. National Institutes of Health. Copyright: Copyright 2014 Elsevier B.V., All rights reserved.",
year = "1987",
month = may,
day = "5",
doi = "10.1016/0006-8993(87)90338-6",
language = "English (US)",
volume = "410",
pages = "357--361",
journal = "Brain Research",
issn = "0006-8993",
publisher = "Elsevier",
number = "2",
}