TY - JOUR
T1 - Serotonin and Acute Ischemic Heart Disease
AU - Hillis, L. David
AU - Lange, Richard A.
PY - 1991/3/7
Y1 - 1991/3/7
N2 - Over the past 10 to 15 years, we have gained considerable insight into the pathophysiology of acute ischemic heart disease, and as a result our therapeutic approach has changed substantially. In the 1960s and early 1970s, Prinzmetal's variant angina, an uncommon entity, was shown to result from transient reductions in myocardial oxygen supply, which were due to vasospasm (often superimposed on a fixed stenosis) of an epicardial coronary artery.1 In contrast, the more common forms of acute ischemic heart disease, such as unstable angina and myocardial infarction, were thought to result from excessive myocardial oxygen demand in the setting of.
AB - Over the past 10 to 15 years, we have gained considerable insight into the pathophysiology of acute ischemic heart disease, and as a result our therapeutic approach has changed substantially. In the 1960s and early 1970s, Prinzmetal's variant angina, an uncommon entity, was shown to result from transient reductions in myocardial oxygen supply, which were due to vasospasm (often superimposed on a fixed stenosis) of an epicardial coronary artery.1 In contrast, the more common forms of acute ischemic heart disease, such as unstable angina and myocardial infarction, were thought to result from excessive myocardial oxygen demand in the setting of.
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U2 - 10.1056/NEJM199103073241008
DO - 10.1056/NEJM199103073241008
M3 - Editorial
C2 - 1994253
AN - SCOPUS:0026081836
VL - 324
SP - 688
EP - 690
JO - New England Journal of Medicine
JF - New England Journal of Medicine
SN - 0028-4793
IS - 10
ER -