Serotonin-3 Receptors in the Actions of Alcohol, Alcohol Reinforcement, and Alcoholism

William J. McBride, David M. Lovinger, Tina Machu, Richard J. Thielen, Zachary A. Rodd, James M. Murphy, John D. Roache, Bankole A. Johnson

Research output: Contribution to journalArticlepeer-review

70 Scopus citations


This article represents the proceedings of a symposium at the 2003 annual meeting of the Research Society on Alcoholism in Fort Lauderdale, FL. The organizers and chairs were William J. McBride and David M. Lovinger. The presentations were (1) Mechanisms of alcohol potentiation of 5-HT3 receptor function, by David M. Lovinger and Tina Machu; (2) Chronic alcohol drinking alters 5-HT3 receptors regulating the mesolimbic dopamine system, by Richard J. Thielen; (3) 5-HT3 receptors in the VTA regulate alcohol drinking and the reinforcing effects of alcohol, by Zachary A. Rodd and James M. Murphy; and (4) Ondansetron as a treatment for "biological" alcoholism, by John D. Roache and Bankole A. Johnson.

Original languageEnglish (US)
Pages (from-to)257-267
Number of pages11
JournalAlcoholism: Clinical and Experimental Research
Issue number2
StatePublished - Feb 2004


  • Alcohol Reinforcement
  • Alcoholism Treatment
  • Mesolimbic Dopamine System
  • Ondansetron
  • Serotonin-3 Receptor

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Medicine (miscellaneous)
  • Toxicology


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