Seroprevalence of 13 common pathogens in a rapidly growing U.S. minority population

Mexican Americans from San Antonio, TX

Rohina Rubicz, Charles T. Leach, Ellen B Kraig, Nikhil V. Dhurandhar, Barry Grubbs, John Blangero, Robert Yolken, Harald Hh Göring

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Background: Infection risks vary among individuals and between populations. Here we present information on the seroprevalence of 13 common infectious agents in a San Antonio-based sample of Mexican Americans. Mexican Americans represent the largest and most rapidly growing minority population in the U.S., and they are also considered a health disparities population. Methods. We analyzed 1227 individuals for antibody titer to Chlamydophila pneumoniae, Helicobacter pylori, Toxoplasma gondii, cytomegalovirus, Epstein-Barr virus, herpes simplex virus-1, herpes simplex virus-2 (HSV-2), human herpesvirus-6 (HHV-6), varicella zoster virus (VZV), adenovirus-36, hepatitis A virus, and influenza A and B. Seroprevalence was examined as a function of sex, age, household income, and education. Results: Seroprevalence estimates ranged from 9% for T. gondii to 92% for VZV, and were similar in both sexes except for HSV-2, which was more prevalent in women. Many pathogens exhibited a significant seroprevalence change over the examined age range (15-94 years), with 7 pathogens increasing and HHV-6 decreasing with age. Socioeconomic status significantly correlated with serostatus for some pathogens. Conclusions: Our findings demonstrate substantial seroprevalence rates of these common infections in this sample of Mexican Americans from San Antonio, Texas that suffers from high rates of chronic diseases including obesity and type-2 diabetes.

Original languageEnglish (US)
Article number433
JournalBMC Research Notes
Volume4
DOIs
StatePublished - 2011

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Seroepidemiologic Studies
Pathogens
Viruses
Human Herpesvirus 6
Human Herpesvirus 3
Human Herpesvirus 2
Population
Toxoplasma
Hepatitis A virus
Chlamydophila pneumoniae
Human Herpesvirus 1
Infection
Cytomegalovirus
Human Herpesvirus 4
Adenoviridae
Helicobacter pylori
Social Class
Type 2 Diabetes Mellitus
Human Influenza
Chronic Disease

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Cite this

Seroprevalence of 13 common pathogens in a rapidly growing U.S. minority population : Mexican Americans from San Antonio, TX. / Rubicz, Rohina; Leach, Charles T.; Kraig, Ellen B; Dhurandhar, Nikhil V.; Grubbs, Barry; Blangero, John; Yolken, Robert; Göring, Harald Hh.

In: BMC Research Notes, Vol. 4, 433, 2011.

Research output: Contribution to journalArticle

Rubicz, Rohina ; Leach, Charles T. ; Kraig, Ellen B ; Dhurandhar, Nikhil V. ; Grubbs, Barry ; Blangero, John ; Yolken, Robert ; Göring, Harald Hh. / Seroprevalence of 13 common pathogens in a rapidly growing U.S. minority population : Mexican Americans from San Antonio, TX. In: BMC Research Notes. 2011 ; Vol. 4.
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abstract = "Background: Infection risks vary among individuals and between populations. Here we present information on the seroprevalence of 13 common infectious agents in a San Antonio-based sample of Mexican Americans. Mexican Americans represent the largest and most rapidly growing minority population in the U.S., and they are also considered a health disparities population. Methods. We analyzed 1227 individuals for antibody titer to Chlamydophila pneumoniae, Helicobacter pylori, Toxoplasma gondii, cytomegalovirus, Epstein-Barr virus, herpes simplex virus-1, herpes simplex virus-2 (HSV-2), human herpesvirus-6 (HHV-6), varicella zoster virus (VZV), adenovirus-36, hepatitis A virus, and influenza A and B. Seroprevalence was examined as a function of sex, age, household income, and education. Results: Seroprevalence estimates ranged from 9{\%} for T. gondii to 92{\%} for VZV, and were similar in both sexes except for HSV-2, which was more prevalent in women. Many pathogens exhibited a significant seroprevalence change over the examined age range (15-94 years), with 7 pathogens increasing and HHV-6 decreasing with age. Socioeconomic status significantly correlated with serostatus for some pathogens. Conclusions: Our findings demonstrate substantial seroprevalence rates of these common infections in this sample of Mexican Americans from San Antonio, Texas that suffers from high rates of chronic diseases including obesity and type-2 diabetes.",
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