Sensitivity of the Common Bile Duct to Acid Peptic Digestion

E. G. Yonehiro; K. Imamoglu; H. D. Root; N. W. Crisp; S. L. Wangensteen; O. H. Wangensteen

doi:10.3181/00379727-97-23706

Sensitivity of the Common Bile Duct to Acid Peptic Digestion

E. G. Yonehiro, K. Imamoglu, H. D. Root, N. W. Crisp, S. L. Wangensteen, O. H. Wangensteen

Research output: Contribution to journal › Article › peer-review

Abstract

1. The glandular mucosa of common bile duct shows a sensitivity to acidpeptic digestion at least as great as that of the esophagus. 2. Admixture of bile and pancreatic juice incubated from 1/2 to 48 hours failed to demonstrate evidence of digestive injury to either the common bile duct or the esophagus during a 2-hour period of perfusion. 3. There would appear to be a possibility that acid-peptic erosion of the biliary papilla may play a role in the genesis of stricture of the bile duct in some disease states.

Original language	English (US)
Pages (from-to)	249-251
Number of pages	3
Journal	Proceedings of the Society for Experimental Biology and Medicine
Volume	97
Issue number	1
DOIs	https://doi.org/10.3181/00379727-97-23706
State	Published - Jan 1958
Externally published	Yes

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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AU - Root, H. D.

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AU - Wangensteen, S. L.

AU - Wangensteen, O. H.

PY - 1958/1

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N2 - 1. The glandular mucosa of common bile duct shows a sensitivity to acidpeptic digestion at least as great as that of the esophagus. 2. Admixture of bile and pancreatic juice incubated from 1/2 to 48 hours failed to demonstrate evidence of digestive injury to either the common bile duct or the esophagus during a 2-hour period of perfusion. 3. There would appear to be a possibility that acid-peptic erosion of the biliary papilla may play a role in the genesis of stricture of the bile duct in some disease states.

AB - 1. The glandular mucosa of common bile duct shows a sensitivity to acidpeptic digestion at least as great as that of the esophagus. 2. Admixture of bile and pancreatic juice incubated from 1/2 to 48 hours failed to demonstrate evidence of digestive injury to either the common bile duct or the esophagus during a 2-hour period of perfusion. 3. There would appear to be a possibility that acid-peptic erosion of the biliary papilla may play a role in the genesis of stricture of the bile duct in some disease states.

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Sensitivity of the Common Bile Duct to Acid Peptic Digestion

Abstract

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