Selective response of lymphocytes from Treponema pallidum infected rabbits to mitogens and Treponema reiteri

C. S. Pavia, J. B. Baseman, J. D. Folds

Research output: Contribution to journalArticle

3 Scopus citations

Abstract

The in vitro response of peripheral blood lymphocytes from rabbits infected with Treponema pallidum was examined using various mitogens and avirulent Treponema reiteri. For the first 4 wk after treponemal infection, the response of lymphocytes from syphilitic rabbits to phytohemagglutinin and pokeweed mitogen was markedly reduced in comparison to uninfected controls. Lymphocytes from both groups of rabbits responded normally to class specific immunoglobulin anti sera (anti immunoglobulin M and anti immunoglobulin G) and T. reiteri.

Original languageEnglish (US)
Pages (from-to)417-422
Number of pages6
JournalInfection and Immunity
Volume15
Issue number2
StatePublished - Jan 1 1977
Externally publishedYes

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ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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