Selective response of lymphocytes from Treponema pallidum infected rabbits to mitogens and Treponema reiteri

C. S. Pavia; J. B. Baseman; J. D. Folds

doi:10.1128/iai.15.2.417-422.1977

Selective response of lymphocytes from Treponema pallidum infected rabbits to mitogens and Treponema reiteri

C. S. Pavia, J. B. Baseman, J. D. Folds

Research output: Contribution to journal › Article › peer-review

Abstract

The in vitro response of peripheral blood lymphocytes from rabbits infected with Treponema pallidum was examined using various mitogens and avirulent Treponema reiteri. For the first 4 wk after treponemal infection, the response of lymphocytes from syphilitic rabbits to phytohemagglutinin and pokeweed mitogen was markedly reduced in comparison to uninfected controls. Lymphocytes from both groups of rabbits responded normally to class specific immunoglobulin anti sera (anti immunoglobulin M and anti immunoglobulin G) and T. reiteri.

Original language	English (US)
Pages (from-to)	417-422
Number of pages	6
Journal	Infection and immunity
Volume	15
Issue number	2
DOIs	https://doi.org/10.1128/iai.15.2.417-422.1977
State	Published - 1977
Externally published	Yes

ASJC Scopus subject areas

Infectious Diseases
Parasitology
Microbiology
Immunology

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10.1128/iai.15.2.417-422.1977

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year = "1977",

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AU - Baseman, J. B.

AU - Folds, J. D.

PY - 1977

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AB - The in vitro response of peripheral blood lymphocytes from rabbits infected with Treponema pallidum was examined using various mitogens and avirulent Treponema reiteri. For the first 4 wk after treponemal infection, the response of lymphocytes from syphilitic rabbits to phytohemagglutinin and pokeweed mitogen was markedly reduced in comparison to uninfected controls. Lymphocytes from both groups of rabbits responded normally to class specific immunoglobulin anti sera (anti immunoglobulin M and anti immunoglobulin G) and T. reiteri.

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Selective response of lymphocytes from Treponema pallidum infected rabbits to mitogens and Treponema reiteri

Abstract

ASJC Scopus subject areas

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