Screening for colorectal cancer.

A. K. Diehl

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Colorectal cancer remains a major cause of mortality in the United States. Of all persons diagnosed with this tumor, less than 50 percent survive five years. Useful preventive measures have not been established. Screening programs, however, offer the prospect of detecting cancers early in their course, when the prognosis for survival is more favorable. To date, no screening test has clearly demonstrated its effectiveness in reducing mortality from colorectal cancer. Periodic rigid sigmoidoscopy and stool occult blood testing have gained many advocates, but have yet to be proved worthwhile in adequately controlled clinical trials. Uncontrolled studies indicate that both these techniques discover approximately 2 cancers per 1000 screenees. There is suggestive evidence that the cancers discovered are more likely to be localized. For the present, physicians should limit colorectal cancer screening to persons at relatively high risk: persons aged over 45 years, with a family history of bowel cancer, or with polyps. Protocols should be designed to ensure high specificity. The recommendations of the National Cancer Institute's consensus conference provide practical guidelines pending the outcome of randomized controlled trials.

Original languageEnglish (US)
Pages (from-to)625-632
Number of pages8
JournalJournal of Family Practice
Volume12
Issue number4
StatePublished - Apr 1981
Externally publishedYes

Fingerprint

Colorectal Neoplasms
Neoplasms
Sigmoidoscopy
Occult Blood
National Cancer Institute (U.S.)
Mortality
Controlled Clinical Trials
Polyps
Early Detection of Cancer
Colonic Neoplasms
Consensus
Randomized Controlled Trials
Guidelines
Physicians
Survival

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Diehl, A. K. (1981). Screening for colorectal cancer. Journal of Family Practice, 12(4), 625-632.

Screening for colorectal cancer. / Diehl, A. K.

In: Journal of Family Practice, Vol. 12, No. 4, 04.1981, p. 625-632.

Research output: Contribution to journalArticle

Diehl, AK 1981, 'Screening for colorectal cancer.', Journal of Family Practice, vol. 12, no. 4, pp. 625-632.
Diehl, A. K. / Screening for colorectal cancer. In: Journal of Family Practice. 1981 ; Vol. 12, No. 4. pp. 625-632.
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