Safety assessment of vitis vinifera (grape)-derived ingredients as used in cosmetics

Monice M. Fiume, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, F. Alan Andersen, Lillian J. Gill

Research output: Contribution to journalReview article

16 Scopus citations

Abstract

The Cosmetic Ingredient Review Expert Panel (Panel) assessed the safety of 24 Vitis vinifera (grape)-derived ingredients and found them safe in the present practices of use and concentration in cosmetics. These ingredients function in cosmetics mostly as skin-conditioning agents, but some function as antioxidants, flavoring agents, and/or colorants. The Panel reviewed the available animal and clinical data to determine the safety of these ingredients. Additionally, some constituents of grapes have been assessed previously for safety as cosmetic ingredients by the Panel, and others are compounds that have been discussed in previous Panel safety assessments.

Original languageEnglish (US)
Pages (from-to)48S-83S
JournalInternational journal of toxicology
Volume33
Issue number6
DOIs
StatePublished - Sep 13 2014

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Keywords

  • Vitis vinifera
  • cosmetics
  • grape
  • safety

ASJC Scopus subject areas

  • Toxicology

Cite this

Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., Marks, J. G., Shank, R. C., Slaga, T. J., Snyder, P. W., Andersen, F. A., & Gill, L. J. (2014). Safety assessment of vitis vinifera (grape)-derived ingredients as used in cosmetics. International journal of toxicology, 33(6), 48S-83S. https://doi.org/10.1177/1091581814545247