Safety Assessment of Cucumis sativus (Cucumber)-Derived Ingredients as Used in Cosmetics

Monice M. Fiume, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, Ronald C. Shank, Thomas J Slaga, Paul W. Snyder, F. Alan Andersen

Research output: Contribution to journalArticle

1 Scopus citations


The CIR Expert Panel assessed the safety of 6 Cucumis sativus (cucumber)-derived ingredients and found them safe in cosmetic formulations in the present practices of use and concentration. These ingredients are reported to function in cosmetics as skin-conditioning agents. Cucumber is a commonly consumed food with no history of significant adverse effects, suggesting that its ingredients should not pose any major safety issues following oral exposure. This assessment focused on the dermal exposure to the low concentrations of these ingredients as used in cosmetics. Some of the constituents of cucumbers have been assessed previously for safe use as cosmetic ingredients.

Original languageEnglish (US)
Pages (from-to)47S-64S
JournalInternational Journal of Toxicology
StatePublished - 2014
Externally publishedYes



  • cosmetics
  • Cucumis sativus (cucumber)-derived ingredients
  • safety

ASJC Scopus subject areas

  • Toxicology

Cite this

Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., Marks, J. G., Shank, R. C., Slaga, T. J., Snyder, P. W., & Andersen, F. A. (2014). Safety Assessment of Cucumis sativus (Cucumber)-Derived Ingredients as Used in Cosmetics. International Journal of Toxicology, 33, 47S-64S.