Safety Assessment of Citrus-Derived Peel Oils as Used in Cosmetics

Christina L. Burnett, Monice M. Fiume, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, Ronald C. Shank, Thomas J Slaga, Paul W. Snyder, Lillian J. Gill, Bart Heldreth

Research output: Contribution to journalArticle

Abstract

The Cosmetic Ingredient Review Expert Panel assessed the safety of 14 citrus-derived peel oil ingredients and concluded that these ingredients are safe for use in cosmetic products when finished products, excluding rinse-off products, do not contain more than 0.0015% (15 ppm) 5-methoxypsoralen, and when formulated to be nonsensitizing and nonirritating. The citrus-derived peel oil ingredients are most frequently reported to function in cosmetics as fragrances and/or skin conditioning agents. The Panel reviewed the available animal and clinical data to determine the safety of these ingredients. Because final product formulations may contain multiple botanicals, each containing the same constituents of concern, formulators are advised to be aware of these constituents and to avoid reaching levels that may be hazardous to consumers. Industry should use good manufacturing practices to limit impurities that could be present in botanical ingredients.

Original languageEnglish (US)
Pages (from-to)33S-59S
JournalInternational journal of toxicology
Volume38
Issue number2
DOIs
StatePublished - Sep 1 2019

Fingerprint

Cosmetics
Citrus
Oils
Safety
Fragrances
Skin
Industry
Animals
Impurities

Keywords

  • citrus peel oils
  • cosmetics
  • safety

ASJC Scopus subject areas

  • Toxicology

Cite this

Burnett, C. L., Fiume, M. M., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... Heldreth, B. (2019). Safety Assessment of Citrus-Derived Peel Oils as Used in Cosmetics. International journal of toxicology, 38(2), 33S-59S. https://doi.org/10.1177/1091581819862504

Safety Assessment of Citrus-Derived Peel Oils as Used in Cosmetics. / Burnett, Christina L.; Fiume, Monice M.; Bergfeld, Wilma F.; Belsito, Donald V.; Hill, Ronald A.; Klaassen, Curtis D.; Liebler, Daniel C.; Marks, James G.; Shank, Ronald C.; Slaga, Thomas J; Snyder, Paul W.; Gill, Lillian J.; Heldreth, Bart.

In: International journal of toxicology, Vol. 38, No. 2, 01.09.2019, p. 33S-59S.

Research output: Contribution to journalArticle

Burnett, CL, Fiume, MM, Bergfeld, WF, Belsito, DV, Hill, RA, Klaassen, CD, Liebler, DC, Marks, JG, Shank, RC, Slaga, TJ, Snyder, PW, Gill, LJ & Heldreth, B 2019, 'Safety Assessment of Citrus-Derived Peel Oils as Used in Cosmetics', International journal of toxicology, vol. 38, no. 2, pp. 33S-59S. https://doi.org/10.1177/1091581819862504
Burnett CL, Fiume MM, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al. Safety Assessment of Citrus-Derived Peel Oils as Used in Cosmetics. International journal of toxicology. 2019 Sep 1;38(2):33S-59S. https://doi.org/10.1177/1091581819862504
Burnett, Christina L. ; Fiume, Monice M. ; Bergfeld, Wilma F. ; Belsito, Donald V. ; Hill, Ronald A. ; Klaassen, Curtis D. ; Liebler, Daniel C. ; Marks, James G. ; Shank, Ronald C. ; Slaga, Thomas J ; Snyder, Paul W. ; Gill, Lillian J. ; Heldreth, Bart. / Safety Assessment of Citrus-Derived Peel Oils as Used in Cosmetics. In: International journal of toxicology. 2019 ; Vol. 38, No. 2. pp. 33S-59S.
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