Safety Assessment of Chlorphenesin as Used in Cosmetics

Wilbur Johnson, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, F. Alan Andersen

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Chlorphenesin functions as a biocide in cosmetics and is used at concentrations up to 0.32% in rinse-off products and up to 0.3% in leave-on products. The Cosmetic Ingredient Review Expert Panel (Panel) noted that chlorphenesin was well absorbed when applied to the skin of rats; however, any safety concern was minimized because available data demonstrated an absence of toxicity. The Panel concluded that chlorphenesin is safe in the present practices of use and concentration.

Original languageEnglish (US)
Pages (from-to)5S-15S
JournalInternational journal of toxicology
Volume33
DOIs
StatePublished - May 2014
Externally publishedYes

Keywords

  • chlorphenesin
  • cosmetics
  • safety

ASJC Scopus subject areas

  • Toxicology

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