Safety Assessment of Barium Sulfate as Used in Cosmetics

Wilbur Johnson, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, Ronald C. Shank, Thomas J Slaga, Paul W. Snyder, Lillian J. Gill, Bart Heldreth

Research output: Contribution to journalArticle

Abstract

The Cosmetic Ingredient Review (CIR) Expert Panel (Panel) reviewed the safety of barium sulfate, which functions as an opacifying agent in cosmetic products and is being used at concentrations up to 0.99% and 37% in rinse-off and leave-on products, respectively. The Panel noted that the history of safe medical use of barium sulfate indicates no significant toxicity concerns relating to systemic exposure to this ingredient. Furthermore, the extensive clinical experience of the Panel, including the results of numerous patch tests, indicates that barium salts do not have the potential to induce sensitization. The Panel noted that since salts of sulfuric acid can be irritating to the skin, cosmetic products containing barium sulfate should be formulated to be nonirritating. The Panel concluded that barium sulfate is safe in cosmetics in the present practices of use and concentration described in this safety assessment when formulated to be nonirritating.

Original languageEnglish (US)
Pages (from-to)5S-11S
JournalInternational Journal of Toxicology
Volume37
Issue number3_suppl
DOIs
StatePublished - Nov 1 2018

Fingerprint

Barium Sulfate
Cosmetics
Safety
Salts
Patch Tests
Barium
Toxicity
Skin
History

Keywords

  • barium sulfate
  • cosmetics
  • safety

ASJC Scopus subject areas

  • Toxicology

Cite this

Johnson, W., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... Heldreth, B. (2018). Safety Assessment of Barium Sulfate as Used in Cosmetics. International Journal of Toxicology, 37(3_suppl), 5S-11S. https://doi.org/10.1177/1091581818799346

Safety Assessment of Barium Sulfate as Used in Cosmetics. / Johnson, Wilbur; Bergfeld, Wilma F.; Belsito, Donald V.; Hill, Ronald A.; Klaassen, Curtis D.; Liebler, Daniel C.; Marks, James G.; Shank, Ronald C.; Slaga, Thomas J; Snyder, Paul W.; Gill, Lillian J.; Heldreth, Bart.

In: International Journal of Toxicology, Vol. 37, No. 3_suppl, 01.11.2018, p. 5S-11S.

Research output: Contribution to journalArticle

Johnson, W, Bergfeld, WF, Belsito, DV, Hill, RA, Klaassen, CD, Liebler, DC, Marks, JG, Shank, RC, Slaga, TJ, Snyder, PW, Gill, LJ & Heldreth, B 2018, 'Safety Assessment of Barium Sulfate as Used in Cosmetics', International Journal of Toxicology, vol. 37, no. 3_suppl, pp. 5S-11S. https://doi.org/10.1177/1091581818799346
Johnson W, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC et al. Safety Assessment of Barium Sulfate as Used in Cosmetics. International Journal of Toxicology. 2018 Nov 1;37(3_suppl):5S-11S. https://doi.org/10.1177/1091581818799346
Johnson, Wilbur ; Bergfeld, Wilma F. ; Belsito, Donald V. ; Hill, Ronald A. ; Klaassen, Curtis D. ; Liebler, Daniel C. ; Marks, James G. ; Shank, Ronald C. ; Slaga, Thomas J ; Snyder, Paul W. ; Gill, Lillian J. ; Heldreth, Bart. / Safety Assessment of Barium Sulfate as Used in Cosmetics. In: International Journal of Toxicology. 2018 ; Vol. 37, No. 3_suppl. pp. 5S-11S.
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