Safety Assessment of Avena sativa (Oat)-Derived Ingredients As Used in Cosmetics

Lillian C. Becker, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, Ronald C. Shank, Thomas J. Slaga, Paul W. Snyder, Lillian J. Gill, Bart Heldreth

Research output: Contribution to journalArticle

Abstract

This is a safety assessment of Avena sativa (oat)–derived ingredients. The reported functions of these ingredients in cosmetics include abrasives, antioxidant, skin conditioning agents, absorbents, and bulking agents. The Panel reviewed relevant animal and human data related to these ingredients. Because final product formulations may contain multiple botanicals, each containing the same constituents of concern, formulators are advised to be aware of these constituents and to avoid reaching levels that may lead to sensitization or other toxic effects. The Panel stated that industry should continue to use good manufacturing practices to limit impurities and concluded that all but one of the Avena sativa (oat)–derived ingredients are safe as cosmetic ingredients in the practices of use and concentration described in this safety assessment when formulated to be nonsensitizing; data are insufficient to come to a conclusion of safety for Avena Sativa (Oat) Meristem Cell Extract.

Original languageEnglish (US)
Pages (from-to)23S-47S
JournalInternational journal of toxicology
Volume38
Issue number3_suppl
DOIs
StatePublished - Nov 1 2019

Fingerprint

Cosmetics
Safety
Poisons
Abrasives
Skin
Animals
Antioxidants
Impurities
Meristem
Cell Extracts
Avena
Industry

Keywords

  • Avena sativa
  • cosmetics
  • oat
  • safety

ASJC Scopus subject areas

  • Toxicology

Cite this

Becker, L. C., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., Liebler, D. C., ... Heldreth, B. (2019). Safety Assessment of Avena sativa (Oat)-Derived Ingredients As Used in Cosmetics. International journal of toxicology, 38(3_suppl), 23S-47S. https://doi.org/10.1177/1091581819889904

Safety Assessment of Avena sativa (Oat)-Derived Ingredients As Used in Cosmetics. / Becker, Lillian C.; Bergfeld, Wilma F.; Belsito, Donald V.; Hill, Ronald A.; Klaassen, Curtis D.; Liebler, Daniel C.; Marks, James G.; Shank, Ronald C.; Slaga, Thomas J.; Snyder, Paul W.; Gill, Lillian J.; Heldreth, Bart.

In: International journal of toxicology, Vol. 38, No. 3_suppl, 01.11.2019, p. 23S-47S.

Research output: Contribution to journalArticle

Becker, LC, Bergfeld, WF, Belsito, DV, Hill, RA, Klaassen, CD, Liebler, DC, Marks, JG, Shank, RC, Slaga, TJ, Snyder, PW, Gill, LJ & Heldreth, B 2019, 'Safety Assessment of Avena sativa (Oat)-Derived Ingredients As Used in Cosmetics', International journal of toxicology, vol. 38, no. 3_suppl, pp. 23S-47S. https://doi.org/10.1177/1091581819889904
Becker LC, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler DC et al. Safety Assessment of Avena sativa (Oat)-Derived Ingredients As Used in Cosmetics. International journal of toxicology. 2019 Nov 1;38(3_suppl):23S-47S. https://doi.org/10.1177/1091581819889904
Becker, Lillian C. ; Bergfeld, Wilma F. ; Belsito, Donald V. ; Hill, Ronald A. ; Klaassen, Curtis D. ; Liebler, Daniel C. ; Marks, James G. ; Shank, Ronald C. ; Slaga, Thomas J. ; Snyder, Paul W. ; Gill, Lillian J. ; Heldreth, Bart. / Safety Assessment of Avena sativa (Oat)-Derived Ingredients As Used in Cosmetics. In: International journal of toxicology. 2019 ; Vol. 38, No. 3_suppl. pp. 23S-47S.
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