Safety Assessment of Amino Acid Alkyl Amides as Used in Cosmetics

Christina L. Burnett, Bart Heldreth, Wilma F. Bergfeld, Donald V. Belsito, Ronald A. Hill, Curtis D. Klaassen, Daniel C. Liebler, James G. Marks, Ronald C. Shank, Thomas J Slaga, Paul W. Snyder, F. Alan Andersen, Lillian J. Gill

Research output: Contribution to journalReview article

2 Citations (Scopus)

Abstract

The Cosmetic Ingredient Review Expert Panel (Panel) reviewed the product use, formulation, and safety data of 115 amino acid alkyl amides, which function as skin and hair conditioning agents and as surfactants - cleansing agents in personal care products. Safety test data on dermal irritation and sensitization for the ingredients with the highest use concentrations, lauroyl lysine and sodium lauroyl glutamate, were reviewed and determined to adequately support the safe use of the ingredients in this report. The Panel concluded that amino acid alkyl amides are safe in the present practices of use and concentration in cosmetics, when formulated to be nonirritating.

Original languageEnglish (US)
Pages (from-to)17S-56S
JournalInternational Journal of Toxicology
Volume36
Issue number1_suppl
DOIs
StatePublished - May 1 2017
Externally publishedYes

Fingerprint

Cosmetics
Amides
Safety
Amino Acids
Sodium Glutamate
Skin
Surface-Active Agents
Detergents
Hair
Lysine
Glutamic Acid
Sodium

Keywords

  • amino acid alkyl amides
  • cosmetics
  • safety

ASJC Scopus subject areas

  • Toxicology

Cite this

Burnett, C. L., Heldreth, B., Bergfeld, W. F., Belsito, D. V., Hill, R. A., Klaassen, C. D., ... Gill, L. J. (2017). Safety Assessment of Amino Acid Alkyl Amides as Used in Cosmetics. International Journal of Toxicology, 36(1_suppl), 17S-56S. https://doi.org/10.1177/1091581816686048

Safety Assessment of Amino Acid Alkyl Amides as Used in Cosmetics. / Burnett, Christina L.; Heldreth, Bart; Bergfeld, Wilma F.; Belsito, Donald V.; Hill, Ronald A.; Klaassen, Curtis D.; Liebler, Daniel C.; Marks, James G.; Shank, Ronald C.; Slaga, Thomas J; Snyder, Paul W.; Andersen, F. Alan; Gill, Lillian J.

In: International Journal of Toxicology, Vol. 36, No. 1_suppl, 01.05.2017, p. 17S-56S.

Research output: Contribution to journalReview article

Burnett, CL, Heldreth, B, Bergfeld, WF, Belsito, DV, Hill, RA, Klaassen, CD, Liebler, DC, Marks, JG, Shank, RC, Slaga, TJ, Snyder, PW, Andersen, FA & Gill, LJ 2017, 'Safety Assessment of Amino Acid Alkyl Amides as Used in Cosmetics', International Journal of Toxicology, vol. 36, no. 1_suppl, pp. 17S-56S. https://doi.org/10.1177/1091581816686048
Burnett CL, Heldreth B, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD et al. Safety Assessment of Amino Acid Alkyl Amides as Used in Cosmetics. International Journal of Toxicology. 2017 May 1;36(1_suppl):17S-56S. https://doi.org/10.1177/1091581816686048
Burnett, Christina L. ; Heldreth, Bart ; Bergfeld, Wilma F. ; Belsito, Donald V. ; Hill, Ronald A. ; Klaassen, Curtis D. ; Liebler, Daniel C. ; Marks, James G. ; Shank, Ronald C. ; Slaga, Thomas J ; Snyder, Paul W. ; Andersen, F. Alan ; Gill, Lillian J. / Safety Assessment of Amino Acid Alkyl Amides as Used in Cosmetics. In: International Journal of Toxicology. 2017 ; Vol. 36, No. 1_suppl. pp. 17S-56S.
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