Síntese de amidas derivadas do ácido 6α,7β-di-hidroxivouacapan-17β-óico isolado dos frutos de Pterodon polygalaeflorus Benth (Leguminosae)

A. L. Teixeira; V. J. Belinelo; G. M. Stefani; G. T. Reis; D. L. Ferreira-Alves; D. Piló-Veloso

Síntese de amidas derivadas do ácido 6α,7β-di-hidroxivouacapan-17β-óico isolado dos frutos de Pterodon polygalaeflorus Benth (Leguminosae)

Translated title of the contribution: Synthesis of amide derivatives of 6α,7β-di-hydroxyvouacapan-17β-oic acid isolated from the Pterodon polygalaeflorus Benth fruits (Leguminosae)

A. L. Teixeira, V. J. Belinelo, G. M. Stefani, G. T. Reis, D. L. Ferreira-Alves, D. Piló-Veloso

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Hydro-alcoholic infusions from fruits of Pterodon polygalaeflorus Benth, commonly known as "Sucupira-Branca", are used in Brazilian folk medicine for rheumatic problems and throat infections. Since it has been verified that furanediterpene 6?,7?-di-hydroxyvouacapan-17?-oic acid (ADV), isolated from the hexane extract of these fruits, presents anti-inflammatory, analgesic, and plant growth regulatory activity, a variety of ADV derivatives has been synthesized with the aim of obtaining more information about the structure-activity relationships of this series of compounds. In this work four new amide (4-7) derivatives of ADV have been synthesized. Their structures were established by spectroscopic data, including 2D-NMR methods.

Translated title of the contribution	Synthesis of amide derivatives of 6α,7β-di-hydroxyvouacapan-17β-oic acid isolated from the Pterodon polygalaeflorus Benth fruits (Leguminosae)
Original language	Portuguese
Pages (from-to)	37-44
Number of pages	8
Journal	Revista Brasileira de Plantas Medicinais
Volume	3
Issue number	2
State	Published - 2001
Externally published	Yes

Keywords

Aminofuranediterpeno
NMR
Pterodon polygalaeflorus
Vouacapnóides

ASJC Scopus subject areas

Pharmacology
Complementary and alternative medicine

Cite this

@article{5bdc2105fe9e4da88af0d58fe9c6c805,

title = "S{\'i}ntese de amidas derivadas do {\'a}cido 6α,7β-di-hidroxivouacapan-17β-{\'o}ico isolado dos frutos de Pterodon polygalaeflorus Benth (Leguminosae)",

abstract = "Hydro-alcoholic infusions from fruits of Pterodon polygalaeflorus Benth, commonly known as {"}Sucupira-Branca{"}, are used in Brazilian folk medicine for rheumatic problems and throat infections. Since it has been verified that furanediterpene 6?,7?-di-hydroxyvouacapan-17?-oic acid (ADV), isolated from the hexane extract of these fruits, presents anti-inflammatory, analgesic, and plant growth regulatory activity, a variety of ADV derivatives has been synthesized with the aim of obtaining more information about the structure-activity relationships of this series of compounds. In this work four new amide (4-7) derivatives of ADV have been synthesized. Their structures were established by spectroscopic data, including 2D-NMR methods.",

keywords = "Aminofuranediterpeno, NMR, Pterodon polygalaeflorus, Vouacapn{\'o}ides",

author = "Teixeira, \{A. L.\} and Belinelo, \{V. J.\} and Stefani, \{G. M.\} and Reis, \{G. T.\} and Ferreira-Alves, \{D. L.\} and D. Pil{\'o}-Veloso",

year = "2001",

language = "Portuguese",

volume = "3",

pages = "37--44",

journal = "Revista Brasileira de Plantas Medicinais",

issn = "1516-0572",

publisher = "Instituto de Biociencias",

number = "2",

}

TY - JOUR

T1 - Síntese de amidas derivadas do ácido 6α,7β-di-hidroxivouacapan-17β-óico isolado dos frutos de Pterodon polygalaeflorus Benth (Leguminosae)

AU - Teixeira, A. L.

AU - Belinelo, V. J.

AU - Stefani, G. M.

AU - Reis, G. T.

AU - Ferreira-Alves, D. L.

AU - Piló-Veloso, D.

PY - 2001

Y1 - 2001

N2 - Hydro-alcoholic infusions from fruits of Pterodon polygalaeflorus Benth, commonly known as "Sucupira-Branca", are used in Brazilian folk medicine for rheumatic problems and throat infections. Since it has been verified that furanediterpene 6?,7?-di-hydroxyvouacapan-17?-oic acid (ADV), isolated from the hexane extract of these fruits, presents anti-inflammatory, analgesic, and plant growth regulatory activity, a variety of ADV derivatives has been synthesized with the aim of obtaining more information about the structure-activity relationships of this series of compounds. In this work four new amide (4-7) derivatives of ADV have been synthesized. Their structures were established by spectroscopic data, including 2D-NMR methods.

AB - Hydro-alcoholic infusions from fruits of Pterodon polygalaeflorus Benth, commonly known as "Sucupira-Branca", are used in Brazilian folk medicine for rheumatic problems and throat infections. Since it has been verified that furanediterpene 6?,7?-di-hydroxyvouacapan-17?-oic acid (ADV), isolated from the hexane extract of these fruits, presents anti-inflammatory, analgesic, and plant growth regulatory activity, a variety of ADV derivatives has been synthesized with the aim of obtaining more information about the structure-activity relationships of this series of compounds. In this work four new amide (4-7) derivatives of ADV have been synthesized. Their structures were established by spectroscopic data, including 2D-NMR methods.

KW - Aminofuranediterpeno

KW - NMR

KW - Pterodon polygalaeflorus

KW - Vouacapnóides

UR - https://www.scopus.com/pages/publications/0034967117

UR - https://www.scopus.com/inward/citedby.url?scp=0034967117&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0034967117

SN - 1516-0572

VL - 3

SP - 37

EP - 44

JO - Revista Brasileira de Plantas Medicinais

JF - Revista Brasileira de Plantas Medicinais

IS - 2

ER -

Síntese de amidas derivadas do ácido 6α,7β-di-hidroxivouacapan-17β-óico isolado dos frutos de Pterodon polygalaeflorus Benth (Leguminosae)

Abstract

Keywords

ASJC Scopus subject areas

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