RP 59500, a new streptogramin highly active against recent isolates of North American staphylococci

Gordon L. Archer, Pierre Auger, Gary V. Doern, Mary Jane Ferraro, Peter C. Fuchs, James H. Jorgensen, Donald E. Low, Patrick R. Murray, L. Barth Reller, Charles W. Stratton, Christine B. Wennersten, Robert C. Moellering

Research output: Contribution to journalArticlepeer-review

32 Scopus citations

Abstract

To assess the potential clinical utility of RP 59500, 10 investigators from separate locations in the United States and Canada each tested ∼200 current isolates of staphylococci (Staphylococcus aureus and coagulase-negative staphylococci by a standard protocol. RP 59500 was highly active (MIC90 ≤ 2 μg/ml) against all strains, including those that were resistant to oxacillin, ciprofloxacin, erythromycin, and spiramycin.

Original languageEnglish (US)
Pages (from-to)223-226
Number of pages4
JournalDiagnostic Microbiology and Infectious Disease
Volume16
Issue number3
DOIs
StatePublished - Jan 1 1993

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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