Abstract
The Wnt signaling pathway is well known to play major roles in skeletal development and homeostasis. In certain aspects, fracture repair mimics the process of bone embryonic development. Thus, the importance of Wnt signaling in fracture healing has become more apparent in recent years. Here, we summarize recent research progress in the area, which may be conducive to the development of Wnt-based therapeutic strategies for bone repair.
Original language | English (US) |
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Pages (from-to) | 666-672 |
Number of pages | 7 |
Journal | BMB Reports |
Volume | 47 |
Issue number | 12 |
DOIs | |
State | Published - 2014 |
Keywords
- Fracture healing
- GSK-3β
- Sost
- Wnt signaling pathway
- β-catenin
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology