Abstract
Chronic infection with the hepatitis C virus (CHC) is associated with physical and mental symptoms including fatigue and depression that adversely affect quality of life. A related complaint, sleep disturbance, has received little attention in the literature, with the exception of sleep changes noted in cirrhosis and end-stage liver disease. We present an overview of studies indicating sleep problems in patients with CHC, with about 60% to 65% of individuals reporting such complaints. Evidence suggests that impairments in sleep quality exist independent of antiviral therapy with interferon-α and prior to advanced stages of liver disease. Further investigation of sleep disturbance in CHC patients with a mild stage of liver disease may provide important information on disease course as well as allow additional opportunities for patient support.
Original language | English (US) |
---|---|
Pages (from-to) | 25-29 |
Number of pages | 5 |
Journal | Current Hepatitis Reports |
Volume | 9 |
Issue number | 1 |
DOIs | |
State | Published - Feb 2010 |
Keywords
- ESLD
- HCV
- Hepatitis C
- Liver disease
- Sleep
ASJC Scopus subject areas
- Hepatology
- Virology