Role of plasma membrane and of cytomatrix in maintenance of intracellular to extracellular ion gradients in chicken erythrocytes

I. L. Cameron, K. E. Hunter, N. K.R. Smith, C. F. Hazlewood, A. Ludany, M. Kellermayer

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Ultrastructural observations in combination with electron probe X‐ray microanalysis on detergent (Brij 58) permeabilized (disruption of the plasma membrane) nucleated chicken erythrocytes support the view that a large fraction of cytoplasmic and nuclear K+ is not freely diffusible and that adsorption of K+ on detergent released mobilizable proteins exists within the cell. The data also suggest that the detergent proteins are normally immobilized by a detergent‐resistant cytoskeleton so that they are not immediately free to diffuse from the cell for several minutes after detergent disruption of the plasma membrane.

Original languageEnglish (US)
Pages (from-to)299-304
Number of pages6
JournalJournal of Cellular Physiology
Volume137
Issue number2
DOIs
StatePublished - Nov 1988
Externally publishedYes

ASJC Scopus subject areas

  • Physiology
  • Clinical Biochemistry
  • Cell Biology

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