Role of Noninvasive Studies in Risk Stratification for Sudden Cardiac Death

Chandra Kunavarapu, Daniel M. Bloomfield

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


Sudden cardiac death (SCD) is one of the leading causes of mortality in developing countries. To prevent SCD, it is crucial to have effective tools for identifying patients at risk, given that there are now effective devices and medications that can prevent SCD. Two noninvasive electrocardiographic tools have been approved by the Food and Drug Administration and are being used clinically for identifying patients at risk for SCD: the signal-averaged electrocardiogram (SAECG) and T-wave alternans (TWA). This article reviews each of these approaches and includes a discussion of the mechanisms and a summary of the clinical studies published to date.

Original languageEnglish (US)
Pages (from-to)192-197
Number of pages6
JournalClinical Cardiology
Issue number4
StatePublished - Apr 2004
Externally publishedYes


  • Heart failure
  • Microvolt T-wave alternans
  • Myocardial infarction
  • Signal-averaged electrocardiogram
  • Sudden cardiac death
  • Ventricular tachycardia

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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