Abstract
Purpose: Epilepsy is a comorbidity of idiopathic autism spectrum disorder. The aim was to characterize the risk and time of second seizure in children with idiopathic autism spectrum disorder. Methods: A retrospective review was performed at the University of Chicago and NorthShore University HealthSystem. Patients with idiopathic autism spectrum disorder, ≥1 seizure, and age 2 to 23 years were included. Results: 153 patients were included; 141 (92%) had a second seizure. The average age at first seizure was 7.14 years (median: 5.08 years) and 8.12 years (median: 7.3 years) at second seizure. Average time between first and second seizure was 7.68 months. Discussion: A high risk of seizure recurrence was found in this population. There was a short time to second seizure, with most having a recurrence within 1 year. These findings may be used to guide therapy in children with autism spectrum disorder and epilepsy.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 876-879 |
| Number of pages | 4 |
| Journal | Journal of Child Neurology |
| Volume | 32 |
| Issue number | 10 |
| DOIs | |
| State | Published - Sep 1 2017 |
| Externally published | Yes |
Keywords
- autism
- developmental delay
- epilepsy
- pediatric
- seizures
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Clinical Neurology