Right hippocampus size is negatively correlated with leptin serum levels in bipolar disorder

Miréia Vianna-Sulzbach; Natalia P. Rocha; Antonio Lucio Teixeira; Eduarda D. Rosa; André A.S. Goldani; Marcia Kauer-Sant'Anna; Clarissa S. Gama

doi:10.1016/j.psychres.2015.09.040

Right hippocampus size is negatively correlated with leptin serum levels in bipolar disorder

Miréia Vianna-Sulzbach
, Natalia P. Rocha
, Antonio Lucio Teixeira
, Eduarda D. Rosa
, André A.S. Goldani
, Marcia Kauer-Sant'Anna
, Clarissa S. Gama

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Obesity is more frequent in bipolar disorder. Adipokines are associated with depression and obesity via the inflammatory process. Twenty-six DSM-IV patients with BD and 39 controls were enrolled to assess the relationship between serum leptin and adiponectin with hippocampal volumes. Among patients, there was a significant negative correlation between right hippocampal volume and serum leptin levels. This result sum for the hypothesis of a pro-inflammatory state associated with BD and the prevalent co-morbid obesity.

Original language	English (US)
Pages (from-to)	719-721
Number of pages	3
Journal	Psychiatry Research
Volume	230
Issue number	2
DOIs	https://doi.org/10.1016/j.psychres.2015.09.040
State	Published - Dec 15 2015
Externally published	Yes

Keywords

Adipokines
Bipolar Disorder
Hippocampal volume

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry

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10.1016/j.psychres.2015.09.040

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@article{23daece938b94cb595201040b59ff7ff,

title = "Right hippocampus size is negatively correlated with leptin serum levels in bipolar disorder",

abstract = "Obesity is more frequent in bipolar disorder. Adipokines are associated with depression and obesity via the inflammatory process. Twenty-six DSM-IV patients with BD and 39 controls were enrolled to assess the relationship between serum leptin and adiponectin with hippocampal volumes. Among patients, there was a significant negative correlation between right hippocampal volume and serum leptin levels. This result sum for the hypothesis of a pro-inflammatory state associated with BD and the prevalent co-morbid obesity.",

keywords = "Adipokines, Bipolar Disorder, Hippocampal volume",

author = "Mir{\'e}ia Vianna-Sulzbach and Rocha, \{Natalia P.\} and Teixeira, \{Antonio Lucio\} and Rosa, \{Eduarda D.\} and Goldani, \{Andr{\'e} A.S.\} and Marcia Kauer-Sant'Anna and Gama, \{Clarissa S.\}",

note = "Publisher Copyright: {\textcopyright} 2015 Elsevier Ireland Ltd.",

year = "2015",

month = dec,

day = "15",

doi = "10.1016/j.psychres.2015.09.040",

language = "English (US)",

volume = "230",

pages = "719--721",

journal = "Psychiatry Research",

issn = "0165-1781",

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number = "2",

}

TY - JOUR

T1 - Right hippocampus size is negatively correlated with leptin serum levels in bipolar disorder

AU - Vianna-Sulzbach, Miréia

AU - Rocha, Natalia P.

AU - Teixeira, Antonio Lucio

AU - Rosa, Eduarda D.

AU - Goldani, André A.S.

AU - Kauer-Sant'Anna, Marcia

AU - Gama, Clarissa S.

PY - 2015/12/15

Y1 - 2015/12/15

N2 - Obesity is more frequent in bipolar disorder. Adipokines are associated with depression and obesity via the inflammatory process. Twenty-six DSM-IV patients with BD and 39 controls were enrolled to assess the relationship between serum leptin and adiponectin with hippocampal volumes. Among patients, there was a significant negative correlation between right hippocampal volume and serum leptin levels. This result sum for the hypothesis of a pro-inflammatory state associated with BD and the prevalent co-morbid obesity.

AB - Obesity is more frequent in bipolar disorder. Adipokines are associated with depression and obesity via the inflammatory process. Twenty-six DSM-IV patients with BD and 39 controls were enrolled to assess the relationship between serum leptin and adiponectin with hippocampal volumes. Among patients, there was a significant negative correlation between right hippocampal volume and serum leptin levels. This result sum for the hypothesis of a pro-inflammatory state associated with BD and the prevalent co-morbid obesity.

KW - Adipokines

KW - Bipolar Disorder

KW - Hippocampal volume

UR - https://www.scopus.com/pages/publications/84947127292

UR - https://www.scopus.com/pages/publications/84947127292#tab=citedBy

U2 - 10.1016/j.psychres.2015.09.040

DO - 10.1016/j.psychres.2015.09.040

M3 - Article

C2 - 26434408

AN - SCOPUS:84947127292

SN - 0165-1781

VL - 230

SP - 719

EP - 721

JO - Psychiatry Research

JF - Psychiatry Research

IS - 2

ER -

Right hippocampus size is negatively correlated with leptin serum levels in bipolar disorder

Abstract

Keywords

ASJC Scopus subject areas

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