Abstract
Obesity is more frequent in bipolar disorder. Adipokines are associated with depression and obesity via the inflammatory process. Twenty-six DSM-IV patients with BD and 39 controls were enrolled to assess the relationship between serum leptin and adiponectin with hippocampal volumes. Among patients, there was a significant negative correlation between right hippocampal volume and serum leptin levels. This result sum for the hypothesis of a pro-inflammatory state associated with BD and the prevalent co-morbid obesity.
Original language | English (US) |
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Pages (from-to) | 719-721 |
Number of pages | 3 |
Journal | Psychiatry Research |
Volume | 230 |
Issue number | 2 |
DOIs | |
State | Published - Dec 15 2015 |
Externally published | Yes |
Keywords
- Adipokines
- Bipolar Disorder
- Hippocampal volume
ASJC Scopus subject areas
- Psychiatry and Mental health
- Biological Psychiatry