Right hippocampus size is negatively correlated with leptin serum levels in bipolar disorder

Miréia Vianna-Sulzbach, Natalia P. Rocha, Antonio Lucio Teixeira, Eduarda D. Rosa, André A.S. Goldani, Marcia Kauer-Sant'Anna, Clarissa S. Gama

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Obesity is more frequent in bipolar disorder. Adipokines are associated with depression and obesity via the inflammatory process. Twenty-six DSM-IV patients with BD and 39 controls were enrolled to assess the relationship between serum leptin and adiponectin with hippocampal volumes. Among patients, there was a significant negative correlation between right hippocampal volume and serum leptin levels. This result sum for the hypothesis of a pro-inflammatory state associated with BD and the prevalent co-morbid obesity.

Original languageEnglish (US)
Pages (from-to)719-721
Number of pages3
JournalPsychiatry Research
Volume230
Issue number2
DOIs
StatePublished - Dec 15 2015
Externally publishedYes

Keywords

  • Adipokines
  • Bipolar Disorder
  • Hippocampal volume

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Biological Psychiatry

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