Rhabdomyosarcoma. From the laboratory to the clinic

Peter J Houghton, D. N. Shapiro, J. A. Houghton

Research output: Contribution to journalReview article

11 Citations (Scopus)

Abstract

The prospect of identifying and developing new agents for treatment of rhabdomyosarcomas is discussed in the light of current prognosis for children with advanced stage disease. Preliminary attempts to identify tumor-specific agents using in vitro cell culture show potential promise, but as yet remain unproven. The more complex system of identifying therapeutically active agents using human tumor xenografts has demonstrated usefulness. The potential problems associated with this system are discussed.

Original languageEnglish (US)
Pages (from-to)349-364
Number of pages16
JournalPediatric Clinics of North America
Volume38
Issue number2
DOIs
StatePublished - Jan 1 1991
Externally publishedYes

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Rhabdomyosarcoma
Heterografts
Neoplasms
Cell Culture Techniques
Therapeutics
In Vitro Techniques

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Rhabdomyosarcoma. From the laboratory to the clinic. / Houghton, Peter J; Shapiro, D. N.; Houghton, J. A.

In: Pediatric Clinics of North America, Vol. 38, No. 2, 01.01.1991, p. 349-364.

Research output: Contribution to journalReview article

Houghton, Peter J ; Shapiro, D. N. ; Houghton, J. A. / Rhabdomyosarcoma. From the laboratory to the clinic. In: Pediatric Clinics of North America. 1991 ; Vol. 38, No. 2. pp. 349-364.
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