Revisiting the neuropsychiatry of Huntington’s disease

Antonio Lucio Teixeira, Leonardo Cruz De Souza, Natalia Pessoa Rocha, Erin Furr-Stimming, Edward C. Lauterbach

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease classified under the choreas. Besides motor symptoms, HD is marked by cognitive and behavioral symptoms, impacting patients’ functional capacity. The progression of cognitive impairment and neuropsychiatric symptoms occur in parallel with neurodegeneration. The nature of these symptoms is very dynamic, and the major clinical challenges include executive dysfunction, apathy, depression and irritability. Herein, we provide a focused updated review on the cognitive and psychiatric features of HD.

Original languageEnglish (US)
Pages (from-to)261-266
Number of pages6
JournalDementia e Neuropsychologia
Volume10
Issue number4
DOIs
StatePublished - Oct 1 2016
Externally publishedYes

Keywords

  • Behavior
  • Cognition
  • Huntington’s disease
  • Neuropsychiatry

ASJC Scopus subject areas

  • Sensory Systems
  • Neurology
  • Geriatrics and Gerontology
  • Clinical Neurology
  • Cognitive Neuroscience

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