Abstract
Huntington’s disease (HD) is an autosomal dominant neurodegenerative disease classified under the choreas. Besides motor symptoms, HD is marked by cognitive and behavioral symptoms, impacting patients’ functional capacity. The progression of cognitive impairment and neuropsychiatric symptoms occur in parallel with neurodegeneration. The nature of these symptoms is very dynamic, and the major clinical challenges include executive dysfunction, apathy, depression and irritability. Herein, we provide a focused updated review on the cognitive and psychiatric features of HD.
Original language | English (US) |
---|---|
Pages (from-to) | 261-266 |
Number of pages | 6 |
Journal | Dementia e Neuropsychologia |
Volume | 10 |
Issue number | 4 |
DOIs | |
State | Published - Oct 1 2016 |
Externally published | Yes |
Keywords
- Behavior
- Cognition
- Huntington’s disease
- Neuropsychiatry
ASJC Scopus subject areas
- Sensory Systems
- Neurology
- Geriatrics and Gerontology
- Clinical Neurology
- Cognitive Neuroscience