Abstract
Retinal homogenates from albino rats were incubated at 37°C, with or without the pineal hormone melatonin, FeSO4, or melatonin plus FeSO4. Melatonin significantly diminished the increase in malonaldehyde + 4-hydroxyalkenals levels, an index of lipid peroxidation, both in the presence as well as in the absence of FeSO4. Melatonin protection against lipid peroxidation is probably due to the newly discovered antioxidant activity of this indolamine.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 151-158 |
| Number of pages | 8 |
| Journal | Neuroscience Research Communications |
| Volume | 17 |
| Issue number | 3 |
| State | Published - 1995 |
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Keywords
- Lipid peroxidation
- Melatonin
- Retina
ASJC Scopus subject areas
- Neuroscience(all)
Cite this
Retinal lipid peroxidation in vitro is inhibited by melatonin. / Chen, L. D.; Melchiorri, D.; Sewerynek, E.; Reiter, Russel J.
In: Neuroscience Research Communications, Vol. 17, No. 3, 1995, p. 151-158.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Retinal lipid peroxidation in vitro is inhibited by melatonin
AU - Chen, L. D.
AU - Melchiorri, D.
AU - Sewerynek, E.
AU - Reiter, Russel J
PY - 1995
Y1 - 1995
N2 - Retinal homogenates from albino rats were incubated at 37°C, with or without the pineal hormone melatonin, FeSO4, or melatonin plus FeSO4. Melatonin significantly diminished the increase in malonaldehyde + 4-hydroxyalkenals levels, an index of lipid peroxidation, both in the presence as well as in the absence of FeSO4. Melatonin protection against lipid peroxidation is probably due to the newly discovered antioxidant activity of this indolamine.
AB - Retinal homogenates from albino rats were incubated at 37°C, with or without the pineal hormone melatonin, FeSO4, or melatonin plus FeSO4. Melatonin significantly diminished the increase in malonaldehyde + 4-hydroxyalkenals levels, an index of lipid peroxidation, both in the presence as well as in the absence of FeSO4. Melatonin protection against lipid peroxidation is probably due to the newly discovered antioxidant activity of this indolamine.
KW - Lipid peroxidation
KW - Melatonin
KW - Retina
UR - http://www.scopus.com/inward/record.url?scp=0028810696&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0028810696&partnerID=8YFLogxK
M3 - Article
VL - 17
SP - 151
EP - 158
JO - Neuroscience Research Communications
JF - Neuroscience Research Communications
SN - 0893-6609
IS - 3
ER -