Retinal lipid peroxidation in vitro is inhibited by melatonin

L. D. Chen; D. Melchiorri; E. Sewerynek; R. J. Reiter

Retinal lipid peroxidation in vitro is inhibited by melatonin

L. D. Chen, D. Melchiorri, E. Sewerynek, R. J. Reiter

Cell Systems & Anatomy

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

Retinal homogenates from albino rats were incubated at 37°C, with or without the pineal hormone melatonin, FeSO₄, or melatonin plus FeSO₄. Melatonin significantly diminished the increase in malonaldehyde + 4-hydroxyalkenals levels, an index of lipid peroxidation, both in the presence as well as in the absence of FeSO₄. Melatonin protection against lipid peroxidation is probably due to the newly discovered antioxidant activity of this indolamine.

Original language	English (US)
Pages (from-to)	151-158
Number of pages	8
Journal	Neuroscience Research Communications
Volume	17
Issue number	3
State	Published - Jan 1 1995

Keywords

Lipid peroxidation
Melatonin
Retina

ASJC Scopus subject areas

Neuroscience(all)

Fingerprint Dive into the research topics of 'Retinal lipid peroxidation in vitro is inhibited by melatonin'. Together they form a unique fingerprint.

Cite this

@article{759d27fecc6140b9b1bbd1044e37c373,

title = "Retinal lipid peroxidation in vitro is inhibited by melatonin",

abstract = "Retinal homogenates from albino rats were incubated at 37°C, with or without the pineal hormone melatonin, FeSO4, or melatonin plus FeSO4. Melatonin significantly diminished the increase in malonaldehyde + 4-hydroxyalkenals levels, an index of lipid peroxidation, both in the presence as well as in the absence of FeSO4. Melatonin protection against lipid peroxidation is probably due to the newly discovered antioxidant activity of this indolamine.",

keywords = "Lipid peroxidation, Melatonin, Retina",

author = "Chen, {L. D.} and D. Melchiorri and E. Sewerynek and Reiter, {R. J.}",

year = "1995",

month = jan,

day = "1",

language = "English (US)",

volume = "17",

pages = "151--158",

journal = "Neuroscience Research Communications",

issn = "0893-6609",

publisher = "John Wiley and Sons Inc.",

number = "3",

}

TY - JOUR

T1 - Retinal lipid peroxidation in vitro is inhibited by melatonin

AU - Chen, L. D.

AU - Melchiorri, D.

AU - Sewerynek, E.

AU - Reiter, R. J.

PY - 1995/1/1

Y1 - 1995/1/1

N2 - Retinal homogenates from albino rats were incubated at 37°C, with or without the pineal hormone melatonin, FeSO4, or melatonin plus FeSO4. Melatonin significantly diminished the increase in malonaldehyde + 4-hydroxyalkenals levels, an index of lipid peroxidation, both in the presence as well as in the absence of FeSO4. Melatonin protection against lipid peroxidation is probably due to the newly discovered antioxidant activity of this indolamine.

AB - Retinal homogenates from albino rats were incubated at 37°C, with or without the pineal hormone melatonin, FeSO4, or melatonin plus FeSO4. Melatonin significantly diminished the increase in malonaldehyde + 4-hydroxyalkenals levels, an index of lipid peroxidation, both in the presence as well as in the absence of FeSO4. Melatonin protection against lipid peroxidation is probably due to the newly discovered antioxidant activity of this indolamine.

KW - Lipid peroxidation

KW - Melatonin

KW - Retina

UR - http://www.scopus.com/inward/record.url?scp=0028810696&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028810696&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:0028810696

VL - 17

SP - 151

EP - 158

JO - Neuroscience Research Communications

JF - Neuroscience Research Communications

SN - 0893-6609

IS - 3

ER -

Retinal lipid peroxidation in vitro is inhibited by melatonin

Abstract

Keywords

ASJC Scopus subject areas

Other files and links

Cite this