Rethinking screening for breast cancer and prostate cancer

Laura Esserman, Yiwey Shieh, Ian Thompson

Research output: Contribution to journalReview article

402 Scopus citations

Abstract

After 20 years of screening for breast and prostate cancer, several observations can be made. First, the incidence of these cancers increased after the introduction of screening but has never returned to prescreening levels. Second, the increase in the relative fraction of early stage cancers has increased. Third, the incidence of regional cancers has not decreased at a commensurate rate. One possible explanation is that screening may be increasing the burden of low-risk cancers without significantly reducing the burden of more aggressively growing cancers and therefore not resulting in the anticipated reduction in cancer mortality. To reduce morbidity and mortality from prostate cancer and breast cancer, new approaches for screening, early detection, and prevention for both diseases should be considered.

Original languageEnglish (US)
Pages (from-to)1685-1692
Number of pages8
JournalJAMA - Journal of the American Medical Association
Volume302
Issue number15
DOIs
StatePublished - 2009

ASJC Scopus subject areas

  • Medicine(all)

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