Resveratrol is a promising agent for colorectal cancer prevention and treatment: Focus on molecular mechanisms

Mohadese Honari, Rana Shafabakhsh, Russel J Reiter, Hamed Mirzaei, Zatollah Asemi

Research output: Contribution to journalReview article

8 Scopus citations

Abstract

Colorectal cancer (CRC) is the third most common cancer and one of the main causes of cancer death entire the world. Environmental, dietary, and lifestyle factors including red meat consumption, cigarette smoking, alcohol intake and family history are the most important risk factors of CRC. Multiple pathways including inflammation, oxidative stress, and apoptosis are involved in its incidence and progression. Resveratrol, a polyphenolic compound, has different pharmacologic functions including anti-inflammation, cancer prevention, lipid-lowering effect, and hypoglycemic effect. Many studies have proved that resveratrol might also represent a chemo preventive effect on CRC. Thus, the aim of the current review is to depict the role of resveratrol in treatment of CRC in a molecular manner.

Original languageEnglish (US)
Article number180
JournalCancer Cell International
Volume19
Issue number1
DOIs
StatePublished - Jul 15 2019

Keywords

  • Anti-inflammatory
  • Anti-oncotic
  • Colorectal cancer
  • Resveratrol

ASJC Scopus subject areas

  • Oncology
  • Genetics
  • Cancer Research

Fingerprint Dive into the research topics of 'Resveratrol is a promising agent for colorectal cancer prevention and treatment: Focus on molecular mechanisms'. Together they form a unique fingerprint.

  • Cite this