Restriction of PGK-B to spermatogenic cells: Evidence from experimentally cryptorchid mice

N. S. Rudolph, J. L. VandeBerg

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The hypothesis that PGK-B, like LDH-C4, is restricted to spermatogenic cells was explored by examining isozyme patterns in testes from mice depleted of germinal cells by surgical cryptorchism. In experimentally cryptorchized C57BL/10Sn males, decline in PGK-B activity paralleled decline in LDH-C4 activity and was correlated with a degeneration of spermatocytes, spermatids, and spermatozoa. Trace amounts of these sperm isozymes found in cryptorchid testes after the depletion of maturing germ cells probably came from degenerated spermatids and spermatocytes and not from somatic testicular cells.

Original languageEnglish (US)
Pages (from-to)341-353
Number of pages13
JournalDevelopmental Genetics
Volume1
Issue number4
StatePublished - 1980
Externally publishedYes

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Spermatocytes
Spermatids
Isoenzymes
Spermatozoa
Testis
Cryptorchidism
Germ Cells
lactate dehydrogenase C4

ASJC Scopus subject areas

  • Cell Biology
  • Developmental Biology
  • Genetics

Cite this

Restriction of PGK-B to spermatogenic cells : Evidence from experimentally cryptorchid mice. / Rudolph, N. S.; VandeBerg, J. L.

In: Developmental Genetics, Vol. 1, No. 4, 1980, p. 341-353.

Research output: Contribution to journalArticle

Rudolph, N. S. ; VandeBerg, J. L. / Restriction of PGK-B to spermatogenic cells : Evidence from experimentally cryptorchid mice. In: Developmental Genetics. 1980 ; Vol. 1, No. 4. pp. 341-353.
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