Restriction of neurogenic ability during neural crest cell differentiation

Kristine S. Vogel, Michael F. Marusich, James A. Weston

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Multipotent neural crest cells undergo developmental restrictions during embryogenesis and eventually give rise to the neurons and glia of the peripheral nervous system, melanocytes, and pheochromocytes. To understand how neuronal potential is restricted to a subpopulation of crest‐derived cells, we have utilized sensitive markers of early neuronal differentiation to assess neurogenesis in crest‐derived cell populations subjected to defined experimental conditions in vitro and in vivo. We describe environmental conditions that either (a) result in the irreversible loss of neurogenic potential over a characteristic time course or (b) maintain neurogenic potential among neural crest cells. © 1993 John Wiley & Sons, Inc.

Original languageEnglish (US)
Pages (from-to)162-171
Number of pages10
JournalJournal of Neurobiology
Issue number2
StatePublished - Feb 1993
Externally publishedYes


  • developmental restrictions
  • neural crest
  • neurogenesis

ASJC Scopus subject areas

  • Cellular and Molecular Neuroscience
  • General Neuroscience


Dive into the research topics of 'Restriction of neurogenic ability during neural crest cell differentiation'. Together they form a unique fingerprint.

Cite this