Response to treatment with antidepressants of patients with severe or moderate nonpsychotic depression and of patients with psychotic depression

J. H. Kocsis, J. L. Croughan, M. M. Katz, T. P. Butler, S. Secunda, C. L. Bowden, J. M. Davis

Research output: Contribution to journalArticle

45 Scopus citations

Abstract

Hospitalized patients were divided into nonpsychotic severely depressed (N = 53), nonpsychotic moderately depressed (N = 54), and psychotic depressed (N = 25) groups and treated with either imipramine or amitriptyline, up to 250 mg/day, for 4 weeks. Good response occurred in 39% of the 38 severely depressed, 67% of the 49 moderately depressed, and 32% of the 19 psychotic depressed patients who completed treatment. The response of the patients with nonpsychotic severe depression did not differ significantly from the response of those with psychotic depression, and both groups fared worse than the group with nonpsychotic moderate depression.

Original languageEnglish (US)
Pages (from-to)621-624
Number of pages4
JournalAmerican Journal of Psychiatry
Volume147
Issue number5
DOIs
StatePublished - 1990

ASJC Scopus subject areas

  • Psychiatry and Mental health

Fingerprint Dive into the research topics of 'Response to treatment with antidepressants of patients with severe or moderate nonpsychotic depression and of patients with psychotic depression'. Together they form a unique fingerprint.

  • Cite this